ReviewTransboundary and emerging diseases2023
Porcine Circovirus Type 3: Diagnostics, Genotyping, and Challenges in Vaccine Development.
Review in Transboundary and emerging diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Establishment of an Indirect ELISA Detection Method for Porcine Circovirus 3 Based on Soluble Cap Protein.Veterinary sciences · 2026Article
- Epidemiological and genetic variation analysis of emerging porcine circovirus type 3 in Henan Province, 2023-2024.BMC veterinary research · 2026Article
- Epidemiological investigation of PCV2 and PCV3 in three provinces of Northeast China in 2025.BMC veterinary research · 2026Article
- Detection of PCV3 in various sample types from wild boars in Poland.BMC veterinary research · 2026Article
- Preparation and immunological effects of a bivalent subunit candidate vaccine based on the PCV-Cap-2-3 gene engineered from baculovirus.Frontiers in veterinary science · 2026Article
- Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review.Transboundary and emerging diseases · 2026Review
- Genetic Characterization and Evidence of Capsid Epitope Variation in Porcine Circovirus Type 3 Strains from Vietnamese Swine with Reproductive Disorders.Current microbiology · 2025Article
- Development of a Highly Specific Monoclonal Antibody-Based Sandwich ELISA for Rapid Detection of Porcine Circovirus Type 3.Viruses · 2025Article
- Exploring viral diversity in diarrheic porcine feces: a metagenomic analysis from an Indian swine farm.Frontiers in cellular and infection microbiology · 2025Article
- A case report of porcine circovirus 3 (PCV3) reproductive disease in Iberian semi-outdoor reared sows.Porcine health management · 2024Article
- Molecular epidemiological surveillance and complete genome analysis of porcine circoviruses in wild boars (Journal of veterinary science · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine circovirus (PCV) comprises four distinct species, namely, PCV1-4, with considerable differences between them, resulting in limited crossprotection. PCV2 inflicts substantial economic losses on the swine industry. PCV3 was found to have been circulating before its discovery in 2015. PCV3 is suspected of having a comparable impact to PCV2; however, its characterization studies are still underway. The symptoms of PCV3 infection are similar to those of PCV2 infection. However, PCV2 and PCV3 share a maximum amino acid identity of only 37%, which partially explains the inadequacy of the PCV2 vaccine in protecting against PCV3 infection. Swift measures must be taken to control PCV3, including vaccine development, as it also poses a threat to swine populations. This review synthesizes the recent findings on PCV3 in comparison with PCV2 and highlights the prevailing challenges encountered in vaccine development. Various strategies and innovative approaches to producing PCV3 vaccines, such as using RNA particle technology and baculovirus vectors, are also discussed. Addressing research gaps in diagnostic methods, viral isolation, and vaccine development is crucial to controlling this virus, which poses a threat to swine populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.