Evidence map›Paper›PMID 40303663›Full record

ArticleTransboundary and emerging diseases2023

Development and Evaluation of the Biological Adjuvant Bivalent Vaccine for Preventing Newcastle Disease and Infectious Bursal Disease.

Xiaochen Guo, Wenying Sun, Changhui Hu, Xiangxiang Wang, Shuang Li, Ruihan Qin, Yixuan Wang, Jinmiao Liu, Zhiqiang Xue, Huijuan Li and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xiaochen GuoBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0002-9911-3026
Wenying SunBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0002-4787-4886
Changhui HuBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0002-5099-132X
Xiangxiang WangBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0001-8092-2408
Shuang LiBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0001-5036-3895
Ruihan QinBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0009-0005-0340-1621
Yixuan WangBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0009-0006-8639-0231
Jinmiao LiuBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0001-6622-4566
Zhiqiang XueBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0003-3424-1198
Huijuan LiBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0003-4789-2926
Tingting ZhangBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0009-0008-2178-8614
Wei WangBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0009-0009-3110-0163
Yunpeng GuoBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0009-0001-1955-2337
Jiechao YinBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0002-3373-7506
Ming JiangBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0001-8427-6909
Han ZhaoBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0002-1633-510X
Lan WeiBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0003-1317-8054
Jingmin ZhangBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0009-0000-3046-2052
Guiping RenBiopharmaceutical Lab, College of Life Science, Northeast Agricultural University, Harbin 150030, China.ORCID https://orcid.org/0000-0001-8202-5380

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newcastle disease (ND) and infectious bursal disease (IBD) are both one of the most economically important infectious diseases, which cause high infection rate and mortality of chickens and restrict the development of the poultry industry. Currently, vaccination is the most effective method to prevent ND and IBD. In this study, the biological adjuvant bivalent vaccine (rClone30-VP2L-chGM-CSF) was developed for preventing ND and IBD. Furthermore, the immune and protective effects of rClone30-VP2L-chGM-CSF were evaluated in specific-pathogen-free chickens. The experimental results indicated that chickens immunized with rClone30-VP2L-chGM-CSF vaccine significantly improved anti-IBDV and anti-NDV antibody titer; the level of CD4

Indexed as

Birnaviridae InfectionsChickensInfectious bursal disease virusNewcastle DiseaseNewcastle disease virusPoultry DiseasesViral VaccinesAdjuvants, ImmunologicAnimalsAntibodies, ViralSpecific Pathogen-Free OrganismsAdjuvants, ImmunologicAntibodies, ViralViral Vaccines

Identifiers

PMID40303663
PMCPMC12017208

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.