Evidence map›Paper›PMID 40303550›Full record

ArticleFrontiers in pediatrics2025

Early-onset neonatal sepsis in a Chinese maternal and child healthcare centre, 2017-2023.

Weilin Wang, Zhenhui Wang, Linghua Wang, Suping Li, Jiangling Liu, Yaqin Huang, Jun Liu, Chun Zhu, Juan Zhang, Cairong Li and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Weilin Wang *Department of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Zhenhui Wang *Department of Obstetrics, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Linghua WangDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Suping LiDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Jiangling LiuDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Yaqin HuangDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Jun LiuDepartment of Clinical Laboratory, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Chun ZhuDepartment of Obstetrics, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Juan ZhangDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Cairong LiDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Chunjia YangDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Qiong ChenDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Wenqin WangDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Shulin DengDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.
Yiming DuDepartment of Neonatology, Hunan Provincial Maternal and Child Health Care Hospital, University of South China, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Early-onset sepsis (EOS) remains an important issue in neonatal units. Characteristics of EOS from China have not been fully revealed yet. Our aim is to investigate epidemiology, microbiology and clinical feature of EOS in a Chinese maternal and child healthcare centre. Methods: This is a retrospective observational study of EOS infants born in or admitted to Hunan Provincial Maternal and Child Health Care Hospital from January 1, 2017 to December 31, 2023. Results: During the study period, there were 131 neonatal infections. The incidence of EOS was 1.12 (95% CI 0.94-1.33) per 1,000 live births or 3.85 (95% CI 3.22-4.56) per 1,000 admissions. Coagulase-negative staphylococci (CoNS) ( Conclusions: We report a high burden of EOS among infants in the maternal and child healthcare centre from China. CoNS was the most frequent pathogen causing EOS. Longitudinal epidemiologic surveillance is required to improve empiric antibiotic treatment of EOS.

Indexed as

antimicrobial resistanceearly-onset sepsisincidencepathogenssurveillance

Identifiers

PMID40303550
PMCPMC12037611

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.