Evidence map›Paper›PMID 40303542›Full record

ArticleCureus2025

Perioperative Hemostasis Management During Open Mitral Valve Replacement in a Patient With Hypoprothrombinemia Secondary to Lupus Anticoagulant.

Obieze Nwanna-Nzewunwa, Tayyaba M Malik, Melissa Bellomy, Yu-Min Shen, Siavosh Saatee, Christopher Heid

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Obieze Nwanna-NzewunwaCardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, USA.
Tayyaba M MalikCardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, USA.
Melissa BellomyAnesthesia and Critical Care, University of Texas Southwestern Medical Center, Dallas, USA.
Yu-Min ShenHematology, University of Texas Southwestern Medical Center, Dallas, USA.
Siavosh SaateeAnesthesia and Critical Care, University of Texas Southwestern Medical Center, Dallas, USA.
Christopher HeidCardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, Dallas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoprothrombinemia is a rare coagulopathy that complicates surgical interventions and is an uncommon manifestation of lupus anticoagulant. Perioperative coagulopathy is a major challenge in cardiac surgery. To our knowledge, the management of cardiac surgery in patients with hypoprothrombinemia has not been described in prior literature. This case report outlines the challenging surgical intervention of mitral valve replacement in a 47-year-old female patient with rheumatic valve disease (RHD) and a rare prothrombin deficiency secondary to lupus anticoagulant. This report details the multidisciplinary perioperative hemostasis management and outcomes.

Indexed as

antiphosphoplipid syndromecardiac surgeryhypoprothrombinemialupus anticoagulantmitral valve replacementperioperative management

Identifiers

PMID40303542
PMCPMC12040429

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.