Evidence map›Paper›PMID 40303490›Full record

ReviewInternational journal of medical sciences2025

Bacterial exotoxins in medicine: potential value and perspectives.

Yuming Xiao, Zhou Yan, Fangyuan Ren, Yurong Tan

Abstract readReview
In one paragraph

Review in International journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuming XiaoCollege of Life Sciences, Hunan Normal University, Changsha 410081, China.
Zhou YanDepartment of Obstetrics, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 410017, China.
Fangyuan RenDepartment of Obstetrics, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou 410017, China.
Yurong TanDepartment of Medical Microbiology, Central South University Changsha 410083, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial exotoxins are protein- or peptide-based substances secreted by bacteria with high toxicity and specificity. They have diverse mechanisms of action on host cells, leading to host injury by destroying the cellular structure or interfering with physiological functions. With the continuous progress in biotechnology, bacterial exotoxins have broad application prospects in immunotherapy, vaccine development, drug design, and other fields. Appropriate modification of exotoxins can lead to the preparation of highly efficient immune agents and targeted drugs, which brings new hope for overcoming difficult diseases. This study provides a comprehensive and in-depth introduction to the application of bacterial exotoxins in the field of medicine and further explores the potential value of bacterial exotoxins, which is expected to make greater contributions to human health in the future.

Indexed as

BacteriaBacterial ToxinsExotoxinsAnimalsHumansImmunotherapyVaccine DevelopmentBacterial ToxinsExotoxinsbacterial exotoxinsdisease diagnosisimmunotherapyimmunotoxinsvaccine development

Identifiers

PMID40303490
PMCPMC12035837

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.