Evidence map›Paper›PMID 40303397›Full record

ArticleFrontiers in immunology2025

Value of animal sepsis research in navigating the translational labyrinth.

Haichao Wang, Alfred Ayala, Monowar Aziz, Timothy R Billiar, Clifford S Deutschman, Samithamby Jeyaseelan, Daolin Tang, Ping Wang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Reframing sepsis research through translational integrative models.Journal of translational internal medicine · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haichao WangThe Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, United States.
Alfred AyalaDivision of Surgical Research, Brown University Health-Rhode Island Hospital, Providence, RI, United States.
Monowar AzizThe Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, United States.
Timothy R BilliarDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA, United States.
Clifford S DeutschmanThe Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, United States.
Samithamby JeyaseelanDepartment of Pathobiological Science, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Daolin TangDepartment of Surgery, UT Southwestern Medical Center, Dallas, TX, United States.
Ping WangThe Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY, United States.

Funding

Mechanisms of Novel Herbal Therapies for Sepsis.R01AT005076 · NCCIH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI WANG, HAICHAO · 2010 to 2023
$4.3M
Targeting ACOD1 to attenuate innate immune responses to lethal infectionsR01GM127791 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Daolin Tang · 2018 to 2026
$2.2M
Mechanisms of Dysregulated Innate Immune Responses to Lethal InfectionsR35GM145331 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI Haichao Wang · 2022 to 2026
$2.1M
NCCIH NIH HHS R01 AT005076NIGMS NIH HHS R01 GM127791NIGMS NIH HHS R35 GM145331
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

animal modelhuman therapyrheumatoid arthritissepsistherapeutic targets

Identifiers

PMID40303397
PMCPMC12037402

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.