Evidence map›Paper›PMID 40303389›Full record

ArticleFrontiers in veterinary science2025

Efficacy of VG26 and K1 acupuncture points in cardiopulmonary resuscitation of neonatal puppies born by cesarean section.

Maria Lucia G Lourenço, Fabíola C Knupp, Keylla Helena N P Pereira, Kárita M Fuchs, Gleice M Xavier, Júlia C Mendonça, Miriam Harumi Tsunemi, Fabiana F Souza, Jean G F Joaquim

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria Lucia G LourençoVeterinary Neonatology Research Group, Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Fabíola C KnuppVeterinary Neonatology Research Group, Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Keylla Helena N P PereiraVeterinary Neonatology Research Group, Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Kárita M FuchsVeterinary Neonatology Research Group, Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Gleice M XavierVeterinary Neonatology Research Group, Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Júlia C MendonçaVeterinary Neonatology Research Group, Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Miriam Harumi TsunemiInstitute of Biosciences, São Paulo State University (UNESP), Botucatu, Brazil.
Fabiana F SouzaDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.
Jean G F JoaquimDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the effects of acupuncture points VG26 and K1 on the reversal of apnea and the elevation of heart and respiratory rates in neonatal dogs after birth. Sixty neonates who were apneic, bradycardic, bradypneic or dyspneic were divided into three groups: VG26 acupuncture point (GVG26), K1 acupuncture point (GK1), and control (CG). Data on heart rate (HR), respiratory rate (RR) and Apgar score were collected. The moments of analysis were after 1 min of tactile respiratory stimulus (M1); after stimulation with the acupuncture points (M2); and 10 min after the last assessment (M3). After the VG26 and K1 were used, a significant increase in HR was observed between M1 and M2, medians (25% quartile-75% quartile), respectively: GVG26 136 and 202 bpm; GK1 147 and 195 bpm; GC 168 and 187 bpm. Significant clinical improvement was also observed in RR, with a median at M1 and M2, respectively: GVG26 16 and 28 mpm; GK1 18 and 32 mpm; GC 32 and 40 mpm. For the Apgar score, significant differences were observed in the mean scores between M1 and M3 in the GVG26, GK1 and CG groups. The VG26 and K1 acupuncture points are effective in neonatal puppies, leading to improvements in the respiratory pattern and increases in the HR, RR and Apgar score, can be used in neonatal resuscitation at birth.

Indexed as

acupuncturecardiopulmonary resuscitationcesarean sectionneonatologyscore Apgar

Identifiers

PMID40303389
PMCPMC12038903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.