Evidence map›Paper›PMID 40303347›Full record

ArticleTheranostics2025

Pharmacological targeting of mitophagy via ALT001 improves herpes simplex virus 1 (HSV1)-mediated microglial inflammation and promotes amyloid β phagocytosis by restricting HSV1 infection.

Soo-Jin Oh, Young Yeon Kim, Ruiying Ma, Seok Tae Choi, Se Myeong Choi, Jong Hyun Cho, Ji-Yeun Hur, Yongjin Yoo, Kihoon Han, Hosun Park and 2 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Emerging mechanisms of ATG8-independent non-canonical autophagy.Journal of physiology and biochemistry · 2026
    Review
  3. Review
  4. Cell death network regulation in HSV infection: immune evasion versus host defense.Apoptosis : an international journal on programmed cell death · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Herpes simplex virus infection and Alzheimer's disease.Frontiers in aging neuroscience · 2026
    Review
  13. Review
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Soo-Jin OhBK21 Graduate Program, Department of Biomedical Sciences, College of Medicine, Seoul, Republic of Korea.
Young Yeon KimDepartment of Translational Biomedical Sciences, Graduate School of Dong-A University, Busan, Republic of Korea.
Ruiying MaBK21 Graduate Program, Department of Biomedical Sciences, College of Medicine, Seoul, Republic of Korea.
Seok Tae ChoiDepartment of Microbiology, College of Medicine, Yeungnam University, Daegu, Republic of Korea.
Se Myeong ChoiDepartment of Medicinal Biotechnology, College of Health Sciences, Dong-A University, Busan, Republic of Korea.
Jong Hyun ChoDepartment of Medicinal Biotechnology, College of Health Sciences, Dong-A University, Busan, Republic of Korea.
Ji-Yeun HurDepartment of Biological Sciences, Ajou University, Suwon, Republic of Korea.
Yongjin YooBK21 Graduate Program, Department of Biomedical Sciences, College of Medicine, Seoul, Republic of Korea.
Kihoon HanBK21 Graduate Program, Department of Biomedical Sciences, College of Medicine, Seoul, Republic of Korea.
Hosun ParkDepartment of Microbiology, College of Medicine, Yeungnam University, Daegu, Republic of Korea.
Jeanho YunDepartment of Translational Biomedical Sciences, Graduate School of Dong-A University, Busan, Republic of Korea.
Ok Sarah ShinBK21 Graduate Program, Department of Biomedical Sciences, College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyloid beta-PeptidesHerpes SimplexHerpesvirus 1, HumanMicrogliaMitophagyPhagocytosisAlzheimer DiseaseAnimalsCoculture TechniquesHumansInflammationMiceMitochondriaNeuronsAmyloid beta-PeptidesALT001alternative mitophagyherpes simplex virus 1 (HSV1)Microglianeurodegeneration

Identifiers

PMID40303347
PMCPMC12036882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.