Evidence map›Paper›PMID 40303321›Full record

ArticleFrontiers in tuberculosis2024

Clinical and laboratory risk factors for pulmonary tuberculosis recurrence in three pooled Indian cohorts.

Sonya Krishnan, Nikhil Gupte, Mandar Paradkar, Akshay Gupte, Mrunmayi Naik, Swapnil Raskar, Nishi Suryavanshi, Neeta Pradhan, Sanjay Gaikwad, Rajesh Karyakarte and 13 more

Abstract read
In one paragraph

Article in Frontiers in tuberculosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Point-of-Care Prediction Tool for Recurrent Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Sonya KrishnanJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Nikhil GupteJohns Hopkins Center for Infectious Diseases in India, Johns Hopkins India, Pune, India.
Mandar ParadkarJohns Hopkins Center for Infectious Diseases in India, Johns Hopkins India, Pune, India.
Akshay GupteDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA.
Mrunmayi NaikJohns Hopkins Center for Infectious Diseases in India, Johns Hopkins India, Pune, India.
Swapnil RaskarJohns Hopkins Center for Infectious Diseases in India, Johns Hopkins India, Pune, India.
Nishi SuryavanshiJohns Hopkins Center for Infectious Diseases in India, Johns Hopkins India, Pune, India.
Neeta PradhanJohns Hopkins Center for Infectious Diseases in India, Johns Hopkins India, Pune, India.
Sanjay GaikwadBJ Government Medical College and Sassoon General Hospitals, Pune, India.
Rajesh KaryakarteBJ Government Medical College and Sassoon General Hospitals, Pune, India.
Rahul LokhandeBJ Government Medical College and Sassoon General Hospitals, Pune, India.
Elizabeth Hanna LukeIndian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, India.
Kannan ThiruvengadamIndian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, India.
Chandrasekaran PadmapriyadarsiniIndian Council of Medical Research, National Institute for Research in Tuberculosis, Chennai, India.
Tushar SahasrabudheDr. D.Y. Patil Medical College, Hospital & Research Centre, Pune, India.
Madhusudan BarthwalDr. D.Y. Patil Medical College, Hospital & Research Centre, Pune, India.
ArjunLal KakraniDr. D.Y. Patil Medical College, Hospital & Research Centre, Pune, India.
Vijay ViswanathanM. V. Hospital for Diabetes, Royapuram, Chennai, India.
Hardy KornfeldDepartment of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Amita GuptaJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Jonathan E GolubCenter for Tuberculosis Research, School of Medicine, Johns Hopkins University, Baltimore, MD.
Vidya MaveJohns Hopkins University School of Medicine, Baltimore, MD, USA.
EDOTS-TBDM-CTRIUMPh-RePORT India Study Team

Funding

The Johns Hopkins Baltimore-Washington-India Clinical Trials Unit (BWI CTU)UM1AI069465 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Charles W. Flexner, Amita Gupta · 2012 to 2026
$34.1M
RESEARCH TRAINING IN MICROBIAL DISEASEST32AI007291 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JOEL N BLANKSON, Sara Elizabeth Cosgrove · 1986 to 2026
$9.1M
The Impact of Diabetes on TB treatment outcomesR01AI097494 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GOLUB, JONATHAN E. · 2013 to 2017
$3.0M
NIAID NIH HHS R01 AI097494NIAID NIH HHS T32 AI007291NIAID NIH HHS UM1 AI069465
6 · The paper itself

Abstract

Some individuals with drug-susceptible pulmonary tuberculosis (PTB) experience tuberculosis recurrence. To evaluate the incidence of and risk factors for recurrence following completion of antituberculosis therapy, we pooled data from three prospective observational Indian PTB cohorts with 1164 individuals ≥14 years old included in our analysis. Ninety-five (8%) experienced recurrence with an 8.5 cases/100 person-years recurrence incidence rate (95% confidence interval 6.9-10.3) and a median time to recurrence of 6 months. On multivariable logistic regression, month 2 culture positivity (aHR 2.06; 95% CI 1.17-3.63), BMI <17 mg/kg

Indexed as

adverse outcomerecurrencerisk factorsTuberculosis

Identifiers

PMID40303321
PMCPMC12040415

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.