ArticleKidney international reports2025
Genotype-Phenotype Correlations in Denys-Drash Syndrome in Children.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07605884 (Post-transplant Lymphoproliferative Disorder Following Kidney Transplantation in Denys-Drash Syndrome), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Post-transplant Lymphoproliferative Disorder Following Kidney Transplantation in Denys-Drash Syndrome: a Case-control Study
Who cites it
5 citing papers in PubMed.
- Characteristics and clinical outcomes of Denys-Drash syndrome: a systematic review of case reports and case series.Pediatric nephrology (Berlin, Germany) · 2026Review
- Kidney transplantation in children with extended ilio-caval thrombosis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Denys-Drash Syndrome byCase reports in endocrinology · 2026Article
- Novel WT1 and ACTN4 co-mutations in a patient with Denys-Drash syndrome and an atypical, potentially attenuated presentation of nephropathy: a case report.BMC nephrology · 2025Article
- WT1-Related Nephropathy in a Phenotypically Female Child: A Case of Clinical and Genetic Discordance.Children (Basel, Switzerland) · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
25 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Denys-Drash syndrome (DDS) is a rare disease typically associated with a triad of early onset nephrotic syndromes (NS), susceptibility to Wilms tumor (WT), and genitourinary structural defects. DDS is caused by Wilms' tumor suppression gene ( Methods: We conducted a national retrospective study of all children diagnosed with a pathogenic variant in Results: Fifty-eight children with DDS and variants in exons 8 ( Conclusion: In our cohort, children's DDS clinical trajectory was associated with exon localization. In the era of genomic newborn screening, depicting genetic risk is of utmost importance for personalized patient care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.