Evidence map›Paper›PMID 40303143›Full record

ArticleTransboundary and emerging diseases2024

Molecular Screening and Characterization of Canine Coronavirus Types I and II Strains from Domestic Dogs in Southern Italy, 2019-2021.

Francesco Mira, Giorgia Schirò, Gianvito Lanave, Gabriele Chiaramonte, Marta Canuti, Elisabetta Giudice, Paolo Capozza, Vincenzo Randazzo, Francesco Antoci, Donato Antonio Raele and 4 more

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Francesco MiraIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0003-1276-0579
Giorgia SchiròIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0003-3323-6653
Gianvito LanaveDepartment of Veterinary Medicine, University of Bari, Strada Provinciale per Casamassima Km 3, Valenzano, Bari 70010, Italy.ORCID https://orcid.org/0000-0003-4614-677X
Gabriele ChiaramonteIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0002-2804-4449
Marta CanutiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Via Francesco Sforza 35, Milano 20122, Italy.ORCID https://orcid.org/0000-0002-9959-128X
Elisabetta GiudiceDepartment of Veterinary Sciences, University of Messina, Viale Palatucci, Messina 98168, Italy.ORCID https://orcid.org/0000-0002-0604-1765
Paolo CapozzaDepartment of Veterinary Medicine, University of Bari, Strada Provinciale per Casamassima Km 3, Valenzano, Bari 70010, Italy.ORCID https://orcid.org/0000-0001-5563-1131
Vincenzo RandazzoIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.
Francesco AntociIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0001-7221-7768
Donato Antonio RaeleIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata, Via Manfredonia 20, Foggia 71121, Italy.ORCID https://orcid.org/0000-0003-2627-0669
Domenico VicariIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0002-8902-6383
Annalisa GuercioIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0003-1042-5355
Nicola DecaroDepartment of Veterinary Medicine, University of Bari, Strada Provinciale per Casamassima Km 3, Valenzano, Bari 70010, Italy.ORCID https://orcid.org/0000-0001-6348-7969
Giuseppa PurpariIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri", Via Gino Marinuzzi 3, Palermo 90129, Italy.ORCID https://orcid.org/0000-0001-7285-5321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine coronavirus (CCoV) is a common agent of gastroenteritis in dogs, although some variants have been found associated with systemic and often fatal diseases. Distinct genotypes (CCoV-I and CCoV-II) and subgenotypes (CCoV-IIa and CCoV-IIb) are worldwide distributed. In Italy, CCoV infections have been occasionally evaluated, but information about the molecular epidemiology and the genomic features of currently circulating strains is limited. This study reports the detection and molecular characterization of CCoV strains from samples collected from 284 dogs in Italy between 2019 and 2021. CCoV RNA was detected in 39 (13.7%) dogs, as a single viral agent (5 animals, 12.8%) or with other viral pathogens (canine parvovirus types 2a/2b/2c; canine adenovirus type 1; norovirus GIV.2) (34 animals, 87.2%). A total of 48 CCoV strains were detected either alone (CCoV-I: 51.3%, CCoV-IIa: 20.5%) or in copresence (CCoV-I and CCoV-IIa, 23.1%); surprisingly, CCoV-IIb was not identified in this study. Five clusters of CCoV-I were detected, and their spike gene sequences showed the highest nucleotide identities with CCoV-I strains collected from Greece in 2008/2009 and from China in 2021. CCoV-IIa spike gene sequences (three variants) had the highest nucleotide identities with CCoV-IIa strains collected in Greece in 2008/2009 and in Italy in 2009/2011. Given the high CCoV diversity and the variable pathogenicity potential, we underline the need of further surveillance studies to increase our understanding of the epidemiology and evolution of these viruses.

Indexed as

Coronavirus, CanineCoronavirus InfectionsDog DiseasesAnimalsDogsGenotypeItalyPhylogeny

Identifiers

PMID40303143
PMCPMC12016997

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.