Evidence map›Paper›PMID 40303137›Full record

ArticleTransboundary and emerging diseases2024

Development of Live Vaccine Candidates for Canine Influenza H3N2 Using Naturally Truncated NS1 Gene.

Jaehyun Hwang, Sun-Woo Yoon, Eulhae Ga, Suyun Moon, Jaeseok Choi, Eunseo Bae, Jung-Ah Kang, Hye Kwon Kim, Dae Gwin Jeong, Daesub Song and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Transboundary and emerging diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jaehyun Hwang *College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID https://orcid.org/0009-0001-5708-4140
Sun-Woo Yoon *Department of Biological Sciences and Biotechnology, Andong National University, Andong 36729, Republic of Korea.ORCID https://orcid.org/0000-0002-1448-4494
Eulhae GaCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID https://orcid.org/0009-0007-5414-0999
Suyun MoonCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID https://orcid.org/0009-0007-6938-1082
Jaeseok ChoiCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID https://orcid.org/0009-0009-5381-0836
Eunseo BaeCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID https://orcid.org/0009-0008-9638-9941
Jung-Ah KangBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Hye Kwon KimDepartment of Biological Sciences and Biotechnology, College of National Sciences, Chungbuk National University, Cheongju 28644, Republic of Korea.
Dae Gwin JeongBionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Daesub SongCollege of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Republic of Korea.ORCID https://orcid.org/0000-0002-2759-1061
Woonsung NaCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID https://orcid.org/0000-0002-7254-5240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The NS1 influenza protein of influenza A virus is a viral nonstructural protein encoded by the NS gene segment that has multiple accessory functions during viral infection. In recent years, the major role ascribed to NS1 has been its inhibition of host immune responses, especially the limitation of both interferon (IFN) production and the antiviral effects of IFN-induced protein. We isolated an equine influenza virus with a naturally truncated NS1 gene in our previous study. In this current research, we inserted this partially truncated NS gene into the H

Indexed as

Dog DiseasesInfluenza A Virus, H3N2 SubtypeInfluenza VaccinesOrthomyxoviridae InfectionsViral Nonstructural ProteinsAnimalsDogsFemaleMadin Darby Canine Kidney CellsMiceMice, Inbred BALB CVaccines, AttenuatedVirus ReplicationInfluenza VaccinesINS1 protein, influenza virusVaccines, AttenuatedViral Nonstructural Proteins

Identifiers

PMID40303137
PMCPMC12017229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.