Influenza A Virus Utilizes the Nasolacrimal System to Establish Respiratory Infection after Ocular Exposure in the Swine Model.

Shubin Li, Xuebin Peng, MinJie Wang, Wenqian Wang, Yuye Liu, Qian Yang

Abstract read

In one paragraph

Article in Transboundary and emerging diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Pathological evidence of neurotropism and oculotropism in wild black-headed gulls naturally infected with H5N1 high pathogenicity avian influenza.Scientific reports · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shubin LiMOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0003-4084-039X

Xuebin PengMOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0002-8110-4137

MinJie WangMOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0009-9331-217X

Wenqian WangMOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0006-9275-1590

Yuye LiuMOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0009-0002-2038-9490

Qian YangMOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University, Nanjing, Jiangsu, China.ORCID https://orcid.org/0000-0002-2349-0028

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus (IAV) can rapidly disseminate among animals through various transmission routes, with emerging evidence suggesting the ocular surface as an important entrance. However, it remains unclear how the virus invades the respiratory tract after ocular exposure. Here, we demonstrated that H1N1 (A/swine/Guangdong/1/2011) utilizes the nasolacrimal system to rapidly spread from the ocular surface to the respiratory tract in the porcine model.

Indexed as

Influenza A Virus, H1N1 SubtypeNasolacrimal DuctOrthomyxoviridae InfectionsRespiratory Tract InfectionsSwine DiseasesAnimalsConjunctivaDisease Models, AnimalSwine

Identifiers

PMID40303109

DOI10.1155/2024/8192499

PMCPMC12016754

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.