Evidence map›Paper›PMID 40303068›Full record

ArticleTransboundary and emerging diseases2024

Effects of the Glycosylation of the HA Protein of H9N2 Subtype Avian Influenza Virus on the Pathogenicity in Mice and Antigenicity.

Bing Liang, Menglu Fan, Qi Meng, Yaping Zhang, Jiayu Jin, Na Chen, Yuanlu Lu, Chenfeng Jiang, Xingxing Zhang, Zongyou Zou and 2 more

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bing LiangMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0009-0004-6501-3571
Menglu FanMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0000-0001-8191-600X
Qi MengMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0009-0006-1005-5648
Yaping ZhangState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute in CAAS, Harbin, China.ORCID https://orcid.org/0009-0007-6477-8769
Jiayu JinMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0009-0000-0131-9791
Na ChenMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0000-0002-0095-8310
Yuanlu LuMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0000-0002-1868-2439
Chenfeng JiangMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0009-0004-1468-7250
Xingxing ZhangMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0009-0007-0777-901X
Zongyou ZouMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0009-0000-9114-4592
Jihui PingMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0000-0003-4583-2575
Juan SuMOE International Joint Collaborative Research Laboratory for Animal Health and Food Safety and Jiangsu Engineering Laboratory of Animal Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.ORCID https://orcid.org/0000-0001-6239-1711

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the H9N2 subtype avian influenza virus (H9N2 AIV) evolves naturally, mutations in the hemagglutinin (HA) protein still occur, which involves some sites with glycosylations. It is widely established that glycosylation of the H9N2 AIV HA protein has a major impact on the antigenicity and pathogenicity of the virus. However, the biological implications of a particular glycosylation modification site (GMS) have not been well investigated. In this study, we generated viruses with different GMSs based on wild-type (WT) viruses. Antigenicity studies revealed that the presence of viruses with a 200G

Indexed as

Hemagglutinin Glycoproteins, Influenza VirusInfluenza A Virus, H9N2 SubtypeOrthomyxoviridae InfectionsAnimalsFemaleGlycosylationInfluenza in BirdsMiceMice, Inbred BALB CVirulenceHemagglutinin Glycoproteins, Influenza Virus

Identifiers

PMID40303068
PMCPMC12016912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.