Evidence map›Paper›PMID 40303056›Full record

ArticleTransboundary and emerging diseases2024

Infectivity and Potential Zoonotic Characteristics of Porcine Pseudorabies Virus in Human Cells.

Xue Li, Nan Li, Jiawei Zheng, Xinru Lv, Yaqi Han, Huimin Zhang, Ying Ren, Gefen Yin, Linzhu Ren

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xue LiCollege of Animal Sciences State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Jilin University, 5333 Xi'an Road, Changchun 130062, China.ORCID https://orcid.org/0000-0003-2485-4812
Nan LiChangchun Veterinary Research Institute Chinese Academy of Agricultural Sciences, 666 Liuying West Road, Changchun 130122, China.ORCID https://orcid.org/0009-0007-2616-4619
Jiawei ZhengCollege of Animal Sciences State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Jilin University, 5333 Xi'an Road, Changchun 130062, China.
Xinru LvCollege of Animal Sciences State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Jilin University, 5333 Xi'an Road, Changchun 130062, China.
Yaqi HanCollege of Animal Sciences State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Jilin University, 5333 Xi'an Road, Changchun 130062, China.
Huimin ZhangCollege of Animal Sciences State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Jilin University, 5333 Xi'an Road, Changchun 130062, China.
Ying RenPublic Computer Education and Research Center Jilin University, 5333 Xi'an Road, Changchun 130062, China.
Gefen YinCollege of Veterinary Medicine Yunnan Agricultural University, Kunming 650201, Yunnan, China.
Linzhu RenCollege of Animal Sciences State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Jilin University, 5333 Xi'an Road, Changchun 130062, China.ORCID https://orcid.org/0000-0002-1092-6435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudorabies virus (PRV) is widely spread, characterized by high contagiousness, high viral load, and strong infectivity, and poses severe threats to the global pig farming industry. Apart from pigs, PRV can also infect several other mammals, including mice, cattle, cats, dogs, and wolves, with diverse clinical symptoms. Notably, approximately more than 20 cases of human PRV infection have been reported in recent years, with fever, seizures, human encephalitis, intraocular inflammation, and severe central nervous system symptoms. However, whether PRV can infect humans or belongs to a zoonotic virus is still controversial. In this study, human neuronal cells were infected with PRV and blindly passaged to obtain human cell-adapted PRV, followed by comparing the characteristics of human cell-adapted PRV and pig-derived PRV

Indexed as

Herpesvirus 1, SuidPseudorabiesSwine DiseasesViral ZoonosesZoonosesAnimalsCell LineHumansMiceSwine

Identifiers

PMID40303056
PMCPMC12016998

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.