Evidence map›Paper›PMID 40303008›Full record

ArticleAphasiology2025

Role of pause duration in primary progressive aphasia.

Roelant Ossewaarde, Yolande Pijnenburg, Antoinette Keulen, Roel Jonkers, Stefan Leijnen

Abstract read
In one paragraph

Article in Aphasiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roelant OssewaardeCenter for Language and Cognition, Research School for Behavioral and Cognitive Neurosciences, University of Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-7036-522X
Yolande PijnenburgAlzheimercentrum UMC Amsterdam, Neurology, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-2464-1905
Antoinette KeulenAlzheimercentrum UMC Amsterdam, Neurology, Amsterdam, The Netherlands.
Roel JonkersCenter for Language and Cognition, Research School for Behavioral and Cognitive Neurosciences, University of Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-0223-1596
Stefan LeijnenInstitute for ICT, HU University of Applied Science, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-4411-649X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: To detect differences in speech fluency in separate primary progressive aphasia syndromes (PPA) using automated analysis techniques. The resulting linguistic features are evaluated for their use in a predictive model to identify common patterns in speakers with PPA. As fluency is observable in audio recordings, its quantification may provide a low-cost instrument that augments spontaneous speech analyses in clinical practice. Methods and Procedures: Speech was recorded in 14 controls, 7 nonfluent variant (nfvPPA) and 8 semantic variant (svPPA) speakers. The recordings were annotated for speech and non-speech with Kaldi, a common toolkit for speech processing software. Variables relating to fluency (pause rate, number of pauses, length of pauses) were analyzed. Outcomes and Results: The best fitting distribution of pause duration was a combination of two Gaussian distributions, corresponding with pause categories Conclusions: Automatic measurements of pause duration show meaningful distinctions across the groups and might provide future aid in clinical assessment.

Indexed as

Aphasia, primary progressive (MeSH ID D018888)automatic fluency assessmentfrontotemporal dementia (MeSH ID D057180)primary progressive nonfluent aphasia (MeSH ID D057178)speech disorders (MeSH ID D013064)

Identifiers

PMID40303008
PMCPMC12036531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.