Evidence map›Paper›PMID 40302968›Full record

ArticlePediatric diabetes2024

"I Think I Could Have Used It Better": Experiences of Youth with High HbA1c Commencing Advanced Hybrid Closed-Loop Therapy in a Clinical Trial Setting-A Qualitative Research.

Alison Roberts, Julie Dart, Selena Lloyd, Keely Bebbington, Janice M Fairchild, Geoffrey R Ambler, Fergus J Cameron, Elizabeth A Davis, Timothy W Jones, Mary B Abraham

Abstract read
In one paragraph

Article in Pediatric diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alison RobertsChildren's Diabetes Centre Telethon Kids Institute The University of Western Australia, Perth, Australia.ORCID 0000-0003-3455-6448
Julie DartChildren's Diabetes Centre Telethon Kids Institute The University of Western Australia, Perth, Australia.ORCID 0000-0003-3035-948X
Selena LloydMurdoch University of Western Australia, Murdoch, Australia.
Keely BebbingtonChildren's Diabetes Centre Telethon Kids Institute The University of Western Australia, Perth, Australia.ORCID 0000-0001-5427-0573
Janice M FairchildDepartment of Endocrinology and Diabetes Women's and Children's Hospital, Adelaide, Australia.
Geoffrey R AmblerInstitute of Endocrinology and Diabetes The Children's Hospital at Westmead The University of Sydney, Sydney, Australia.ORCID 0000-0003-0579-3452
Fergus J CameronDepartment of Endocrinology and Diabetes Royal Children's Hospital, Melbourne, Australia.
Elizabeth A DavisChildren's Diabetes Centre Telethon Kids Institute The University of Western Australia, Perth, Australia.
Timothy W JonesChildren's Diabetes Centre Telethon Kids Institute The University of Western Australia, Perth, Australia.
Mary B AbrahamChildren's Diabetes Centre Telethon Kids Institute The University of Western Australia, Perth, Australia.ORCID 0000-0002-3628-1735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Advanced hybrid closed-loop (AHCL) therapy improves glycemia. However, it is not known if there is an improvement in overall outcomes with AHCL for youth with type 1 diabetes (T1D) at high risk of diabetes-related complications. The study aimed to capture the experiences of youth with suboptimal glycemic control when commencing AHCL therapy in a clinical trial setting. Methods: This was a singlecenter substudy of a multicenter 6-month randomized clinical trial. Youth between 12 and 25 years of age on insulin pump therapy with HbA1c > 8.5% (> 69 mmol/mol) who commenced AHCL therapy with Medtronic MiniMed™ system were invited to participate in a semistructured interview after 6 months of AHCL. Open-ended questions were used to explore the participants' lived experience of AHCL in improving their glucose levels and its impact on diabetes management and well-being. The interviews were audiorecorded, transcribed, and analyzed using thematic analysis. Results: Ten youth with T1D with a mean (SD) age of 17.4 (2.9) years, diabetes duration 10.7 (4.8) years, HbA1c 10.2 (0.8)%, or 87 (9.5) mmol/mol at enrollment participated in the interview. Three main themes were identified: (1) improved glycemia despite not using closed loop to its full potential; (2) persistent diabetes burden; and (3) a need for increased psychosocial and clinical support. Although improved glycemia was noted with AHCL therapy, participants reported ongoing motivation issues and used the system suboptimally. They continued to experience distress with overall diabetes management and acknowledged the need for ongoing support from family and health professionals. Conclusion: All participants reported overall satisfaction with improved glucose levels, however, the persistent diabetes burden impacted their ability to use AHCL optimally. The need for ongoing monitoring with support and interventions to enhance psychological care remains vital for youth with suboptimal diabetes management.

Indexed as

Diabetes Mellitus, Type 1Glycated HemoglobinHypoglycemic AgentsInsulinInsulin Infusion SystemsAdolescentAdultBlood GlucoseChildFemaleGlycemic ControlHumansMaleMulticenter Studies as TopicQualitative ResearchRandomized Controlled Trials as TopicBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulin

Identifiers

PMID40302968
PMCPMC12016831

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.