Evidence map›Paper›PMID 40302893›Full record

ArticleWomen (Basel, Switzerland)2025

Association Between Severity of COVID-19 and Social Determinants of Health with Adverse Pregnancy Outcomes in a Study of Mother-Infant Pairs in Los Angeles, California.

Sarah Daouk, Tara Kerin, Trevon Fuller, Olivia Man, Mary C Cambou, Viviana Fajardo-Martinez, Sophia Paiola, Thalia Mok, Rashmi Rao, Karin Nielsen-Saines

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Women (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah DaoukDepartment of Pediatrics, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Tara KerinDepartment of Pediatrics, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Trevon FullerInstitute of the Environment and Sustainability at the University of California, Los Angeles, CA 90095, USA.
Olivia ManDavid Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Mary C CambouDepartment of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Viviana Fajardo-MartinezDepartment of Pediatrics, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Sophia PaiolaDepartment of Pediatrics, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Thalia MokDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.
Rashmi RaoDepartment of Obstetrics and Gynecology, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.ORCID 0000-0002-3407-648X
Karin Nielsen-SainesDepartment of Pediatrics, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA.ORCID 0000-0002-1742-5211

Funding

SARS-CoV-2 in Pregnancy: Comparison of Natural Infection and Hybrid Immunity in Mother-Infant PairsK23AI177952 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Mary Catherine Cambou · 2023 to 2026
$814k
Infant Immunologic and Neurologic Development following Maternal Infection in Pregnancy during Recent EpidemicsR56AI172252 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JUNG, JAE U, NIELSEN, KARIN · 2023 to 2023
$370k
NIAID NIH HHS K23 AI177952NIAID NIH HHS R56 AI172252
6 · The paper itself

Abstract

Previous cross-sectional studies have investigated social determinants of health (SDOH) among pregnant women with COVID-19. However, there are scant data on the impact of these determinants on maternal outcomes from cohorts of pregnant women with COVID-19. We evaluated the association between social determinants of health and both COVID-19 severity and adverse pregnancy outcomes (APOs) in a cohort of pregnant women in Los Angeles (L.A.) County, California. The APOs considered were fetal loss, gestational hypertensive disorders, prolonged rupture of membranes, and maternal death. We recruited pregnant women with confirmed SARS-CoV-2 and collected data on maternal COVID-19 severity, trimester at diagnosis, comorbidities, mode of delivery, COVID-19 vaccination, APOs, maternal age, medical insurance type, race/ethnicity, and neighborhood income. Participants who were obese were more likely to experience severe COVID-19 (OR: 3.61, 95% CI: 1.44-9.46), while even one vaccine dose before COVID-19 infection was associated with reduced odds of severe disease (OR:0.14, 95% CI: 0.02-0.52). Pregnant participants living in low-income areas were more likely to experience APOs (

Indexed as

adverse pregnancy outcomesCOMP cohortCOVID-19 severitypregnancysocial determinants of health

Identifiers

PMID40302893
PMCPMC12037175

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.