Evidence map›Paper›PMID 40302889›Full record

ArticleJournal of orthodontic science2025

Volumetric pulpal changes in permanent first molars following AdvanSyncTM and Twin Block functional appliance: A CBCT study.

Raj K Verma, Sanjeev Verma, Satinder P Singh, Vinay Kumar, Anjana Rajagopalan, Naveen K Subbaiah, Chaman Lal

Abstract read
In one paragraph

Article in Journal of orthodontic science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raj K VermaUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Sanjeev VermaUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Satinder P SinghUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Vinay KumarUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Anjana RajagopalanUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Naveen K SubbaiahUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Chaman LalUnit of Orthodontics and Dentofacial Deformities, Oral Health and Sciences Centre (OHSC), Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDental pulp may respond differently to adverse orthodontic forces. Major physiological effects of optimum orthodontic force application on dental pulp are vascular pulpal changes, pulpal calcification, and fibrosis. Functional appliances taking anchorage from the dentition tend to exert reciprocal higher orthodontic forces.

objectiveTo evaluate the 3D volumetric changes of the dental coronal pulp of maxillary and mandibular permanent first molars 6 months after AdvanSync MATERIALS AND

methodsThis retrospective study was performed on CBCT records obtained from a previous prospective study (Randomized Clinical Trial) comprising 32 patients [females: 17 (9.0-14.5 years), males: 15 (10.5-15.0 years)] who underwent functional mandibular advancement with Twin Block (group 1) and AdvanSync

resultsIntragroup volumetric pulpal changes showed a significant decrease in #16, #26, and #36 at time intervals T0-T1, T0-T2, and T1-T2 in groups 1 and 2. Intergroup comparison of pulpal volume for #16 and #26 was statistically significant at T1. A statistically significant decrease in pulpal volume for #46 was observed at time intervals T0-T1, T0-T2, and T1-T2 in both groups.

conclusionFunctional appliance therapy with both Twin Block and AdvanSync

Indexed as

AdvanSyncCBCTfunctional appliancepulp responseTwin Block

Identifiers

PMID40302889
PMCPMC12036751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.