Evidence map›Paper›PMID 40302755›Full record

ArticleTransboundary and emerging diseases2025

Evaluation of a Luminex-Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal.

Safietou Sankhe, Maryam Diarra, Mamadou Aliou Barry, Martin Faye, Cheikh Talla, Diogop Camara, Maimouna Mbanne, Pape Mbacke Sembene, Amadou Alpha Sall, Gamou Fall and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Safietou SankheVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0001-8559-2161
Maryam DiarraEpidemiology, Clinical Research and Data Science Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0001-9110-4435
Mamadou Aliou BarryEpidemiology, Clinical Research and Data Science Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0002-3956-8782
Martin FayeVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0003-3207-6344
Cheikh TallaEpidemiology, Clinical Research and Data Science Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0003-0678-1226
Diogop CamaraVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Maimouna MbanneVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Pape Mbacke SembeneAnimal Biology Department, Université Cheikh Anta Diop de Dakar, Dakar, Senegal.
Amadou Alpha SallVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Gamou FallVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0001-5035-1325
Oumar FayeVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0002-3478-1322
Cheikh LoucoubarEpidemiology, Clinical Research and Data Science Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0002-9582-4197
Ousmane FayeVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.
Ines Vigan-WomasImmunophysiopathology and Infectious Diseases Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0001-7848-9297
Keersten Michelle RicksDiagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.ORCID https://orcid.org/0000-0002-2854-9308
Jessica Radzio-BasuHuck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-0395-0736
Moussa Moise DiagneVirology Department, Institut Pasteur de Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0001-5461-5623

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and throughput, cost efficiency, and multiplexing capacity is critical. In this work, we evaluated a Luminex-based multiplex microsphere immunoassay for five hemorrhagic fever viruses (HFVs) among the World Health Organization (WHO) blueprint. This five-plex MagPix immunoassay confirmed the presence of Rift Valley fever and Crimean-Congo hemorrhagic fever, but also revealed the exposure of human populations to hantaviruses in Senegal, underscoring the importance of regular serosurveillance in the identification of HFV hotspots.

Indexed as

Hemorrhagic Fevers, ViralOrthohantavirusAnimalsAntibodies, ViralHumansImmunoassaySenegalAntibodies, ViralELISAhemorrhagic fever virusesMagPixSenegalserosurveillanceWest Africa

Identifiers

PMID40302755
PMCPMC12016757

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.