Evidence map›Paper›PMID 40302726›Full record

ArticleOpen forum infectious diseases2025

Comprehensive Care for People Who Use Drugs: Combining Infectious Diseases Services, Harm Reduction, and Primary Care.

Ryan D Knodle, Sarah E Messmer, Albert L Murphy, Renata O Smith, Michael Huyck, Karen Cotler, Antonio D Jimenez, Stockton M Mayer

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryan D KnodleDivision of Infectious Diseases, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-8703-9658
Sarah E MessmerDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-9509-3219
Albert L MurphyCommunity Outreach Intervention Projects, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.
Renata O SmithSection of Infectious Diseases Pharmacotherapy, Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, Illinois, USA.
Michael HuyckDepartment of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-9363-7876
Karen CotlerCollege of Nursing, University of Illinois at Chicago, Chicago, Illinois, USA.
Antonio D JimenezCommunity Outreach Intervention Projects, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA.
Stockton M MayerDivision of Infectious Diseases, University of Illinois at Chicago, Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: People who use drugs (PWUD) have not only increased risk of infectious diseases but also low uptake of primary care. Community-based harm reduction (HR) programs are trusted sources of care among this vulnerable population. Expansion of services offered through these programs may improve access and engagement; we assessed uptake of services within a pilot program in Chicago that offered comprehensive primary care, infectious diseases consultation, and substance use disorder (SUD) and HR services. Methods: PWUD seeking HR services were referred by outreach workers with lived SUD experiences to primary care and infectious diseases providers embedded in the HR program. We reviewed all clinical encounters occurring from 19 October 2018 to 31 December 2021. We assessed patient demographics and visit types and determined the number of encounters for those with and without SUD. We compared characteristics of encounters for individuals with and without SUD using χ Results: Over the study period, services were rendered to 552 unique patients in 1720 clinical encounters. Patients were predominantly male (70.7%), their median age was 43 years (IQR, 19-71), and 75.2% had public insurance. Care for active SUD made up a sizable majority of encounters (n = 1227, 71.3%), and nearly a quarter of these addressed infections often associated with PWUD. Encounters addressing hepatitis C and HIV represented 20% of all encounters. Conclusions: Colocating primary care and infectious diseases services in a community-based HR program in Chicago allowed for high utilization of critical health care offerings by PWUD. This comprehensive care model helps address the unique needs of this population while mitigating common barriers to care.

Indexed as

bloodborne viral pathogenscommunity engagementharm reductionprimary caresubstance use disorder

Identifiers

PMID40302726
PMCPMC12039805

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.