ArticleOpen forum infectious diseases2025
Association of Magnetic Resonance Imaging-Guided Management With Reamputation Rates in Diabetic Foot Osteomyelitis.
Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
Background: Diabetic foot infections constitute 20% of hospital admissions and are the underlying cause of 80% of amputations annually. Staging magnetic resonance imaging (MRI) may decrease reamputation rates in diabetic foot osteomyelitis. Methods: A retrospective chart review was conducted to analyze the risk of reamputation in patients with diabetic foot osteomyelitis hospitalized between 2005 and 2022. MRI-guided therapy and proximal surgical margin pathologic evidence of osteomyelitis were compared. The primary outcome was the rate of reamputation up to 365 days. Results: Enrollment consisted of 386 veterans with a diabetic foot infection complicated by osteomyelitis that required initial amputation, of which 110 patients required reamputation. MRI-guided therapy occurred in 89 of these patients. Preoperative MRI and subsequent MRI-guided therapy were associated with a significant decrease in the chance of reamputation for up to a year after the initial amputation as compared with non-MRI-guided therapy (14/89 [15.7%] vs 96/297 [32.3%], respectively; Conclusions: These findings support that incorporating preamputation MRI and MRI-guided therapy into the diagnostic and treatment approach for diabetic foot osteomyelitis may reduce the risk for subsequent amputations over 1 year.
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