Evidence map›Paper›PMID 40302531›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2026

Cleft Lip and/or Palate Is Associated with an Increased Prevalence of Mental Health and Behavioral Disorders.

F Jeffrey Lorenz, Cheng Ma, Aniruddha C Parikh, Jessyka G Lighthall

Abstract read
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Positive Longitudinal Caregiver Behavioral Ratings and Self-Reported Quality of Life in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

F Jeffrey LorenzDepartment of Otolaryngology-Head and Neck Surgery, Penn State Hershey Medical Center, Hershey, PA, USA.ORCID 0000-0001-5902-7054
Cheng MaDepartment of Otolaryngology-Head and Neck Surgery, Penn State Hershey Medical Center, Hershey, PA, USA.
Aniruddha C ParikhDepartment of Otolaryngology-Head and Neck Surgery, Penn State Hershey Medical Center, Hershey, PA, USA.
Jessyka G LighthallDepartment of Otolaryngology-Head and Neck Surgery, Penn State Hershey Medical Center, Hershey, PA, USA.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

ObjectiveTo evaluate the prevalence of mental health and behavioral disorders in individuals with cleft lip and/or palate (CL/P) versus the general population.DesignRetrospective cohort study. Cohorts of people with CL/P ≤ 18 and >18 years of age were compared to controls matched for age and sex.Setting92 healthcare organizations.Patients, ParticipantsThe TriNetX Research Network was queried for pediatric and adult participants using diagnosis and procedure codes from 2011 to 2021.Main Outcome Measure(s)Rates of mental health disorders and prescriptions for mental health medications and stimulants.ResultsPediatric (

Indexed as

Cleft LipCleft PalateMental DisordersAdolescentAdultCase-Control StudiesChildChild, PreschoolCohort StudiesFemaleHumansMaleMiddle AgedPrevalenceYoung Adultcleft lipcleft palatepsychosocial adjustmentquality of lifesocial support

Identifiers

PMID40302531
PMCPMC12700003

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.