Evidence map›Paper›PMID 40302422›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2025

Study on ABUS Applicability for Rural Women With Low Health Resources in China-Large-Scale Population, Non-Opportunistic Screening.

Meili Niu, Jie Zheng, Xiaoyang Feng, Huijiao Yan, Mengmeng Jia, Shuzhen Qi, Youlin Qiao, Fanghui Zhao, Xiangxian Feng, Zhifang Li

Abstract read
In one paragraph

Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meili NiuSchool of Public Health, Shanxi Medical University, Taiyuan, China.ORCID https://orcid.org/0009-0001-3416-9678
Jie ZhengSchool of Nursing, Changzhi Medical College, Changzhi, China.
Xiaoyang FengSchool of Nursing, Changzhi Medical College, Changzhi, China.
Huijiao YanSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Mengmeng JiaSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Shuzhen QiWomen's Health Care Department, Zezhou Maternal and Child Health Hospital, Jincheng, China.
Youlin QiaoCenter for Global Health, School of Population Medicine and Public Health Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Fanghui ZhaoSchool of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xiangxian FengDepartment of Public Health and Prevention, Changzhi Medical College, Changzhi, China.
Zhifang LiDepartment of Public Health and Prevention, Changzhi Medical College, Changzhi, China.

Funding

Scientific Research task of the Belt and Road Initiative by the Chinese Academy of Medical Sciences: Cooperative Research on the Etiology, Prevention and Control of Cervical Cancer, Breast Cancer, and Esophageal CancerTencent Sustainable Social Value Inclusive Health Lab and the Chongqing Tencent Sustainable Development Foundation: Comprehensive Prevention and Control Demonstration Project for Eliminating Cervical Cancer and Breast Cancer in Low Health Resource Areas of China SD20240904145730
6 · The paper itself

Abstract

objectivesComparing the screening performance of different breast cancer screening methods and exploring the applicability of automated breast ultrasonography (ABUS) in rural areas with low health resources in China.

methodsWomen aged 35-64 underwent hand-held ultrasonography (HHUS) and ABUS in Zezhou County, Jincheng City, Shanxi Province, China from 2018 to 2021. Additionally, women aged 45-69 were also screened with mammography (MG). We compared the 3 methods' cancer detection rates, diagnostic accuracy, and overall screening performance, stratified by age groups and breast density. The chi-square test was used to analyze indicators such as sensitivity, specificity, and referral rate.

resultsThe mean age of the 9100 women studied was 45 ± 6.42 years, and 25 cases of breast cancer were identified (2.72‰). The proportion of dense breasts is higher among women aged 45-64 years (67.52%). Compared to the non-dense breast group, the detection rate of breast cancer by MG is significantly reduced in the dense breast group (3.42‰ versus 1.97‰). The diagnostic accuracy rate of ABUS and HHUS for lesions is higher than that of MG (P < .05). The kappa coefficient indicates moderate agreement in diagnostic results between HHUS and ABUS. However, the agreement between HHUS/ABUS and MG is poor. There were no statistical differences in sensitivity and specificity among the 3 screening methods. The referral rate and NNR for ultrasound were lower than those for MG (P < .05), but there were no statistically significant differences between ABUS and HHUS.

conclusionsAmong women with denser breasts, ultrasound has a higher diagnostic accuracy rate compared to MG, and it avoids unnecessary biopsies. Compared to HHUS, ABUS can diagnose malignant tumors more objectively and standardized.

Indexed as

Breast NeoplasmsEarly Detection of CancerMass ScreeningRural PopulationUltrasonography, MammaryAdultAgedBreastBreast DensityChinaFemaleHealth ResourcesHumansMammographyMiddle AgedSensitivity and Specificityautomatic breast ultrasoundbreast cancertraditional handheld ultrasound

Identifiers

PMID40302422
PMCPMC12327175

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.