Evidence map›Paper›PMID 40302310›Full record

ArticleJournal of neuroendocrinology2025

PRRT plus holmium-166-SIRT (HEPAR PLuS) versus PRRT-only in patients with metastatic neuroendocrine tumors: A propensity-score matched analysis.

W B Veldhuis, T Walter, D M V de Vries-Huizing, J Theysohn, S Barton, E D Ekkelenkamp, B Lachachi, R J G de Jong, L W van Golen, H Lanzafame and 5 more

Abstract readMulticenter StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroendocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

W B VeldhuisDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
T WalterDepartment of Oncology, Hospices Civils de Lyon, Lyon, France.ORCID 0000-0002-4199-4561
D M V de Vries-HuizingDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
J TheysohnDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
S BartonBarton Biostatistics Ltd, Essex, UK.
E D EkkelenkampMedical Affairs Interventional Oncology, Terumo Europe NV, Leuven, Belgium.
B LachachiDepartment of Nuclear Medicine, Hospices Civils de Lyon, Lyon, France.
R J G de JongMedical Affairs Interventional Oncology, Terumo Europe NV, Leuven, Belgium.
L W van GolenDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
H LanzafameClinic for Nuclear Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
L MilotDepartment of Radiology, Hospices Civils de Lyon, Lyon, France.
H LahnerDepartment of Endocrinology and Metabolism, Division of Laboratory Research, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
M E G H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
M E T TesselaarDepartment of Gastrointestinal and Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
A J A T BraatDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-8824-8697

Funding

Terumo
6 · The paper itself

Abstract

Patients with bulky neuroendocrine liver metastases (NELM) undergoing PRRT with [

Indexed as

BrachytherapyHolmiumLiver NeoplasmsNeuroendocrine TumorsRadioisotopesAdultAgedFemaleHumansMaleMiddle AgedOctreotidePropensity ScoreRetrospective StudiesHolmiumHolmium-166OctreotideRadioisotopes166Ho‐SIRT[177Lu]Lu‐DOTATATEneuroendocrine tumorPRRTradioembolization

Identifiers

PMID40302310
PMCPMC12358199

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.