Evidence map›Paper›PMID 40302196›Full record

ArticleNeurointervention2025

Procedure Time of Endovascular Thrombectomy as Performance Measure of Acute Stroke Treatment.

Eung-Joon Lee, Han-Yeong Jeong, Jayoun Kim, Nan Hee Park, Min Kyoung Kang, Dongwhane Lee, Jinkwon Kim, Yo Han Jung, Sungwook Yu, Wook-Joo Kim and 10 more

Abstract read
In one paragraph

Article in Neurointervention, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Eung-Joon LeeDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Han-Yeong JeongDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Jayoun KimMedical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Nan Hee ParkMedical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Min Kyoung KangDepartment of Neurology, Seoul Chuk Hospital, Seoul, Korea.
Dongwhane LeeDepartment of Neurology, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.
Jinkwon KimDepartment of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.
Yo Han JungDepartment of Neurology, Gangnam Severance Hospital, Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Korea.
Sungwook YuDepartment of Neurology, Korea University Medical Center, Seoul, Korea.
Wook-Joo KimDepartment of Neurology, Ulsan University Hospital, Ulsan, Korea.
Han-Jin ChoDepartment of Neurology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Kyungbok LeeDepartment of Neurology, Soon Chun Hyang University Seoul Hospital, Seoul, Korea.
Tai Hwan ParkDepartment of Neurology, Seoul Medical Center, Seoul, Korea.
Mi Sun OhDepartment of Neurology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Ji Sung LeeClinical Research Center, Asan Medical Center, Seoul, Korea.
Joon-Tae KimDepartment of Neurology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.
Byung-Woo YoonDepartment of Neurology, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.
Jong-Moo ParkDepartment of Neurology, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Korea.
Hee-Joon BaeDepartment of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Keun-Hwa JungDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Funding

Korea National Institute of Health 2023-ER1006-02
6 · The paper itself

Abstract

purposeProcedure time (PT), defined as the time between groin access and vessel recanalization, is a recently recognized predictor of outcomes after endovascular thrombectomy (EVT) for acute ischemic stroke (AIS). However, the factors affecting PT and its potential value as a performance measure of AIS treatment remain unexplored. MATERIALS AND

methodsUsing the Korean Stroke Registry, we compared patients who underwent EVT for AIS from 2018 to 2022 based on 60 minutes PT. We conducted multivariate analysis to investigate whether PT <60 minutes was associated with successful recanalization and good functional stroke outcomes. We also investigated factors that independently predicted PT ≥60 minutes. Furthermore, we determined the cutoff point for PT.

resultsWe analyzed 4,703 patients (mean age: 69.5±11.9, 60.3% male) who underwent EVT. The mean PT was 54.6±36.7 minutes. Multivariate analysis revealed that PT <60 minutes independently predicted a good functional outcome as represented by modified Rankin Scale scores of 0-2 (adjusted odds ratio [aOR]: 1.40, 95% confidence interval [CI]: 1.22-1.59). PT <60 minutes was significantly associated with successful recanalization after adjusting for confounding variables (aOR: 1.66, 95% CI: 1.33-2.07). Moreover, after adjusting for covariates, age≥65 years (aOR: 1.20, 95% CI: 1.05-1.38), onset-to-door time (aOR: 1.03, 95% CI: 1.01-1.04), door-to-puncture time (aOR: 1.05, 95% CI: 1.03-1.06), posterior circulation stroke (PCS) (aOR: 1.13, 95% CI: 1.02-1.28), and smoking (aOR: 1.24, 95%CI: 1.09-1.45) independently predicted PT ≥60 minutes. Finally, the highest aOR for good stroke outcome was observed in the 60-minute cutoff model (aOR: 1.45, 95%CI: 1.27-1.67).

conclusionPT <60 minutes was significantly associated with good functional outcomes. Conversely, PT ≥60 minutes was associated with older age, PCS, smoking, prolonged onset-to-door and door-to-puncture time. Further studies are necessary to develop refining strategies for optimizing PT to improve stroke outcomes.

Indexed as

Ischemic strokeOperative timeRegistriesThrombectomy

Identifiers

PMID40302196
PMCPMC12183367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.