SynthesisEuropean journal of oral sciences2025
Effect of mussel-inspired primers on resin-dentin bonding interface stability: A systematic review and meta-analysis.
Synthesis in European journal of oral sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of mussel-inspired compounds on dentin bonding: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Effect of mussel-inspired primers on resin-dentin bonding interface stability: A systematic review and meta-analysis.European journal of oral sciences · 2025Pooled it
- Bioinspired bioadhesion: translating nature's adhesive strategies into regenerative medicine.Med-X · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
This paper presents the results of a systematic review and meta-analysis on the efficacy of mussel-inspired primers on resin-dentin bond stability. This review was registered on the OSF platform (https://doi.org/10.17605/OSF.IO/QC7VU) and followed PRISMA guidelines. Databases included PubMed, SCOPUS, Web of Science, EMBASE, Lilacs, LIVIVO, and gray literature. Eligibility criteria included in vitro studies using human dentin, which assessed bond strength through microtensile tests after applying mussel-inspired primers. Exclusion criteria were studies evaluating bond strength to enamel, animal dentin, and ceramics, those not using the microtensile test, or those conducting immediate evaluation only. The RoBDEMAT tool was used for risk-of-bias analysis. Two independent reviewers screened 5522 articles, and seven were selected. The studies showed a similar risk of bias performance, with insufficient reporting of different parameters, while not presenting significant publication bias. Meta-analysis revealed significantly higher bond strength in specimens treated with mussel-inspired monomers after thermocycling. Across studies, no substantial reduction in heterogeneity was observed using the leave-one-out method. Mussel-inspired monomers incorporated into the dentin adhesive procedure can enhance bond strength, mainly through their catecholic groups, highlighting their potential in adhesive dentistry. However, drawbacks such as oxidative potential and effects on the degree of conversion may limit their widespread application.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.