Evidence map›Paper›PMID 40301812›Full record

ArticleBMC gastroenterology2025

Epidemiological status of family-based Helicobacter pylori infection in Yunnan Province, China.

Ying Wan, Yongmei Wu, Yunran Yang, Qingqing Zhou, Yu Li, Da Wang, Dan Zhang, Kunpeng Na, Lan Liu, Yule He and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ying WanDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.ORCID http://orcid.org/0009-0007-0270-5038
Yongmei WuSchool of Public Health, Kunming Medical University, Yunnan Provincial Key Laboratory of Public Health and Biosafety, 650500, Kunming, China.
Yunran YangUniversity of Toronto, M5S 2E4, Toronto, Canada.
Qingqing ZhouDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.
Yu LiDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.
Da WangDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.
Dan ZhangDepartment of Gastroenterology, Dali Prefecture People's Hospital, 671003, Dali, China.
Kunpeng NaDepartment of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, 650032, Kunming, China.
Lan LiuSchool of Public Health, Kunming Medical University, Yunnan Provincial Key Laboratory of Public Health and Biosafety, 650500, Kunming, China.
Yule HeDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.
Hang ChenDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.
Minshan HuangDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China.
Le CaiSchool of Public Health, Kunming Medical University, Yunnan Provincial Key Laboratory of Public Health and Biosafety, 650500, Kunming, China. caile002@hotmail.com.ORCID http://orcid.org/0000-0001-7315-8077
Dingyun YouSchool of Public Health, Kunming Medical University, Yunnan Provincial Key Laboratory of Public Health and Biosafety, 650500, Kunming, China. youdingyun@kmmu.edu.cn.ORCID http://orcid.org/0000-0002-3830-1891
Lanqing MaDepartment of Gastroenterology, The First Affiliated Hospital, Yunnan Institute of Digestive Disease, Yunnan Clinical Research Center for Digestive Diseases, Kunming Medical University, 650032, Kunming, China. malanqing@aliyun.com.ORCID http://orcid.org/0000-0002-9738-9934

Funding

Yunnan Leading Talent Programme L-2019024
6 · The paper itself

Abstract

backgroundThe status of family-based H. pylori infection in Yunnan Province is unknown. This study is the first family-based epidemiological survey of H. pylori in the province, aiming to provide new insights into the status of family-based H. pylori infections in Yunnan Province as well as in the country as a whole.

methodsBetween 2021 and 2023, 1,176 families with 2,947 family members were tested for H. pylori in six cities in Yunnan Province with different geographic locations and economic status, to assess the status of H. pylori infection, and to clarify the related factors and modes of transmission by means of a questionnaire survey.

resultsIn Yunnan Province, the H. pylori infection rate was 31.46% (927/2947) in people and 54.59% (642/1176) in families.On the individual side, living outside of southern Yunnan (e.g., Central OR 1.41, 95% CI 1.10-1.81), having a family member living together for ≥ 1 year (OR 2.43, 95% CI 1.49-3.95), being ≥ 18 years old (e.g., 18-44 years old: OR 3.51, 95% CI 1.98-6.23), and gastrointestinal discomfort within the last 1 year (OR 1.25, 95% CI 1.04-1.50) were independent risk factors for H. pylori infection in the study population in Yunnan Province, whereas an education level of college/university and above (OR 0.62, 95% CI 0.48-0.79), and a gastroscopy within 5 years (OR 0.58, 95% CI 0.46-0.73) were independent protective factors for their H. pylori infection. In terms of family, living outside of southern Yunnan (e.g., Central OR 1.52, 95% CI 1.07-2.18), and having ≥ 3 people living together in the family (e.g., 3-4 people: OR 2.04, 95% CI 1.52-2.72) were independent risk factors for H. pylori infection in study families in Yunnan Province, whereas an annual household income of ≥ 100,000 ( OR 0.68, 95% CI 0.51-0.90), total household living area ≥ 60 m2 (OR 0.62, 95% CI 0.39-0.97), the use of separate meals for intra-household gatherings (OR 0.56, 95% CI 0.38-0.85), and the use of communal spoons and chopsticks (OR 0.38, 95% CI 0.28-0.52) were the independent protective factorse.

conclusionThe risk factors of Family-Based H. pylori infection in Yunnan province were closely related to demographic characteristics, personal and family living habits. Close contact with infected family members may be the main cause of transmission. Family-based control of H. pylori infection should be regarded in clinical practice.

Indexed as

Helicobacter InfectionsHelicobacter pyloriAdolescentAdultAgedChildChild, PreschoolChinaFamilyFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsSurveys and QuestionnairesEpidemiologicalEthnic minorityFamily-basedHelicobacter pyloriRisk factors

Identifiers

PMID40301812
PMCPMC12039176

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.