Evidence map›Paper›PMID 40301790›Full record

ArticleBMC musculoskeletal disorders2025

Morphologic and morphometric bilateral analysis and sexual dimorphism in sciatic nerves of adult cadaveric specimens in Uganda.

Eric Simidi Kegoye, Abdulfatai Olakunle Ojewale, Winnie Ezekiel, Ibe Michael Usman, Eric Osamudiamwen Aigbogun, Adesanya Olamide Adewale, Edgar Mario Fernandez, Keneth Iceland Kasozi, Halima Nalugo, Isaac Echoru and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eric Simidi KegoyeDepartment of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus, P.O Box 71, Ishaka, Bushenyi, Uganda. ekegoye@gmail.com.
Abdulfatai Olakunle OjewaleDepartment of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus, P.O Box 71, Ishaka, Bushenyi, Uganda.
Winnie EzekielDepartment of Internal Medicine, Faculty ofMedicine, Kampala International University Teaching Hospital, P.O Box 71, Ishaka, Bushenyi, Uganda.
Ibe Michael UsmanDepartment of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus, P.O Box 71, Ishaka, Bushenyi, Uganda.
Eric Osamudiamwen AigbogunDepartment of Human Anatomy, Enugu State University of Science and Technology , PMB 01660, Enugu, Nigeria.
Adesanya Olamide AdewaleDepartment of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus, P.O Box 71, Ishaka, Bushenyi, Uganda.
Edgar Mario FernandezDepartment of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus, P.O Box 71, Ishaka, Bushenyi, Uganda.
Keneth Iceland KasoziDepartment of Physiology, School of Medicine, Kabale University, P.O Box 317, Kabale, Uganda.
Halima NalugoDepartment of Anatomy, Histology and Embryology, Faculty of Medicine, Mbarara University of Science and Technology, P.O Box 1410, Mbarara, Uganda.
Isaac EchoruDepartment of Anatomy, School of Medicine, Kabale University, P.O Box 317, Kabale, Uganda.
Adam Moyosore AfodunDepartment of Anatomy and Cell Biology, Faculty of Health Sciences, Busitema University, P.O. Box 236, Tororo, Uganda.
Ritah KenganziParaMed Home Health Care, 250 Sidney Street, Belleville, ON, K8P 3Z3, Canada.
Okeniran Olatayo SegunDepartment of Anatomy, Faculty of Biomedical Sciences, Kampala International University, Western Campus, P.O Box 71, Ishaka, Bushenyi, Uganda.
Fred SsempijjaInfection Medicine, Edinburgh Medical School, Deanery of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, EH8 9JZ, Edinburgh, Scotland, UK. ssempijjafred.fs@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Sciatic nerve (SN) exhibits distinct sex and side-related differences, which have significant implications for clinical practice. The study investigated the sex and side-related morphologic and morphometric variations of the nerve using cadavers.

methodsThis is a cross-sectional cadaveric study involving 62 Ugandan cadavers. Continuous variables were reported using descriptive statistics and discrete variables were reported as percentages. Ordinary two-way ANOVA was used to compare the dimensions and proportion of the patterns of the SN.

resultsThe study identified six categories of exit patterns of the SN, type A ("Below and undivided") occurred in a majority of cases (62.9%). A penta-furcate branching pattern dominated the whole population. Bifurcate termination pattern was found in most SNs (90.3% and 87.1% for right and left limbs respectively) while the rest have the trifurcate termination pattern, with no side or sex-related variations. The average dimensions of SN were within normal ranges, and showed no side-related differences but with a sex difference (significantly higher in males than females), mean length of the SN in centimetres (length A: Males, right limbs = 30.58 ± 9.00; left limbs = 31.30 ± 6.20; Females, right = 26.07 ± 6.58; left = 26.30 ± 5.56). The difference in the length "A" for the males left limb and females right limb was statistically significant with a p-value of 0.0195.

conclusionsMost of the examined SNs showed normal anatomical characteristics with rare cases of sex-related dimorphism in the termination level and morphometry (length and diameter) of the nerve. The observed sexual dimorphisms in sciatic nerves are of clinical and surgical interest; hence, suggesting the need for further investigations in different populations, especially using advanced techniques such as ultrasonography anatomic techniques.

Indexed as

Sciatic NerveSex CharacteristicsAdultAgedAged, 80 and overCadaverCross-Sectional StudiesFemaleHumansMaleMiddle AgedUgandaAnatomic variationsCadaveric sciatic nervesSciatic nerve dimensionsSciatic nerve dimorphismSciatic nerve injurySciatic nerve patternsSciatic nerve topographySciatic nerve variantUgandan population

Identifiers

PMID40301790
PMCPMC12039151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.