Evidence map›Paper›PMID 40301748›Full record

SynthesisBMC gastroenterology2025

Endoscopic ultrasound-guided ethanol vs ethanol combined with paclitaxel for the ablation of pancreatic cystic lesions: a systematic review and meta-analysis.

Cong Ding, Jianfeng Yang, Jing Yang, Qiang Liu, Yishen Mao, Qi Ding, Ye Gu, Xiaofeng Zhang

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cong DingDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Jianfeng YangDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Jing YangDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Qiang LiuDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Yishen MaoDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Qi DingDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Ye GuDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China.
Xiaofeng ZhangDepartment of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, NO.261 Huansha Road, Hangzhou, Zhejiang, China. zhangxfmed@163.com.

Funding

Key R&D Program of Zhejiang Province No.2023C03054 No.2024C03048
6 · The paper itself

Abstract

backgroundSome pancreatic cystic lesions (PCLs) have the risk of malignant transformation, but the complications of pancreatic surgery are high, and minimally invasive treatment is imperative. Endoscopic ultrasound (EUS) -guided ablation has been utilized to treat pancreatic cysts. We undertook the meta-analysis and systematic review to assess the efficacy and safety of this technique in PCLs.

methodsMEDLINE, Embase, Cochrane Library databases were searched for relevant studies reporting on EUS-guided ablation on PCLs with outcomes of interest. The primary outcome was complete cyst resolution rate, and secondary outcome was adverse events rate.

resultsEleven studies (1092 patients with 1093 PCLs) were selected. Pooled complete cyst resolution rate was 52.6% (95%CI: 41.1-64.1%; I

conclusionsEUS-guided ablation appears to be a minimally invasive treatment with an acceptable efficacy and safety. Ethanol-sequenced paclitaxel is superior to ethanol alone in terms of efficacy and safety for PCLs ablation, but there is no statistical difference; more perfect studies are needed to verify these in the future. PROSPERO REGISTRATION NUMBER: CRD42024583031.

Indexed as

Ablation TechniquesEndosonographyEthanolPaclitaxelPancreatic CystHumansTreatment OutcomeUltrasonography, InterventionalEthanolPaclitaxelAblationEndoscopic ultrasoundEthanolPaclitaxelPancreatic cyst

Identifiers

PMID40301748
PMCPMC12039226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.