Evidence map›Paper›PMID 40301738›Full record

ArticleBMC gastroenterology2025

Prevalence of H. Pylori in inflammatory bowel disease patients and its association with severity.

Abdullah D Alotaibi, Abdullah A Al-Abdulwahab, Mona H Ismail, Jaber M AlElyani, Turki A Alamri, Raed M Alsulaiman, Ibrahim A Alhafid, Ibrahim M Alzahrani, Reem S AlSulaiman, Arwa Althubaity and 3 more

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In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. To eradicate or not?Frontiers in medicine · 2026
    Pooled it
  2. The Controversies in the Relationship BetweenJournal of clinical medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Abdullah D AlotaibiDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia. adotaibi@iau.edu.sa.
Abdullah A Al-AbdulwahabDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Mona H IsmailDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Jaber M AlElyaniDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Turki A AlamriDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Raed M AlsulaimanDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Ibrahim A AlhafidDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Ibrahim M AlzahraniDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Reem S AlSulaimanDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia. rsolaiman615@gmail.com.
Arwa AlthubaityDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Sarah H BuhulaigahDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Abdulaziz A AlQurainDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.
Abdulaziz M AlrezukDepartment of Internal Medicine, College of Medicine, Imam Abdulrahman Bin Faisal university, Dammam, Eastern Province, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOne key area of interest in gastroenterology research is the relationship between Helicobacter pylori (H. pylori) and Inflammatory bowel disease (IBD). Several studies have shown varying results regarding the prevalence of H. pylori in IBD patients and its impact on disease progression, severity, and overall outcome.

methodThis is a prospective cohort study conducted at King Fahad University Hospital in Al Khobar, Saudi Arabia from November 2023 to May 2024 to determine the prevalence of H. pylori in IBD patients and its association with severity. The study included 2 arms for comparison which are IBD patients and control group, IBD will be further classified to CD and UC. Prevalence of H. pylori infection and severity of the disease was compared between these groups.

resultsA total of 360 patients were included in the study which were divided equally into IBD group and control group. The IBD was subdivided into CD with 91 cases and UC with 89 cases. H. Pylori was significantly higher in control group (23.3%) compared with UC cases (13.2%) p value: 0.048. H. pylori infection was significantly high in smokers p value = < 0.0001. The presence of autoimmune disease was significantly associated with H. Pylori infection (16.4%) p value: 0.023.

conclusionH. pylori infection was significantly higher in the control group in comparison to IBD group. In addition, smoking and autoimmune disease were significantly associated with H. pylori infection. Finally, the overall association between severity of CD, UC and medication use with H. Pylori were insignificant.

Indexed as

Colitis, UlcerativeCrohn DiseaseHelicobacter InfectionsHelicobacter pyloriInflammatory Bowel DiseasesAdultCase-Control StudiesFemaleHumansMaleMiddle AgedPrevalenceProspective StudiesSaudi ArabiaSeverity of Illness IndexCrohn’s diseaseHelicobacter pylori infectionPrevalenceUlcerative colitis

Identifiers

PMID40301738
PMCPMC12042615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.