ArticleNature nanotechnology2025
Nanofabrication of silk microneedles for high-throughput micronutrient delivery and continuous sap monitoring in plants.
Article in Nature nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Bioelectronic Considerations in Biomedical Microneedles.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Biosensor-Integrated Microneedle Devices for Diagnosis and Treatment of Chronic and Infectious Diseases: Current Status, Trends and Challenges.Biosensors · 2026Review
- From conceptual design to translational progress: Emerging advances in intelligent microneedles for biomedical applications.Acta pharmaceutica Sinica. B · 2026Review
- Printing technologies for monitoring crop health.Nature communications · 2026Review
- Evolution of 3D-Printed Microneedles toward Closed-Loop Theranostic Platforms.Research (Washington, D.C.) · 2026Review
- Microneedle-Assisted Cell Delivery and Therapy.Research (Washington, D.C.) · 2026Review
- Microneedle Sensors for Ion Monitoring in Plants. One Step Closer to Smart Agriculture.ACS sensors · 2025Review
- Advances in Microneedle Drug Delivery for Obesity: Mechanisms, Applications, and Perspectives.International journal of nanomedicine · 2025Review
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Biomaterials bridging the biotic-abiotic interface in plants offer the opportunity to precisely deliver agrochemicals and continuously monitor plant health, with the goals of increasing resilience to climate change, enhancing crop production and mitigating environmental impact. In this study we report the manipulation of silk fibroin assembly with inorganics nucleation at their phase front to nanomanufacture porous and hollow microneedles that can be interfaced with plants. Plant growth analysis and quantification of wounding gene expression show a non-significant systemic wounding response to the injection of silk microneedles in tomato plants. Microneedles with a hollow structure enable the systemic delivery of plant micronutrients to treat chlorosis in tomato plants and crop biofortification through transport of human micronutrients injected in the petiole and loaded into tomato fruits. Hollow microneedles also provide access to plant vasculature for sap sampling, enabling continuous monitoring and early detection of phytoaccumulation of environmental contaminants such as cadmium.
Indexed as
Identifiers
40301677What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.