ArticleScientific reports2025
Analysis of adverse sagittal alignment after anterior cervical discectomy and fusion (ACDF) for degenerative cervical myelopathy with local kyphosis.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of skip-level ACDF vs. contiguous ACDF in the treatment of skip-level cervical degenerative disease: a systematic review and meta-analysis.Frontiers in surgery · 2026Pooled it
- Differential Impact of C2-7 Sagittal Vertical Axis on Postoperative Axial Symptoms in Laminoplasty vs Laminectomy With Fusion: A Propensity Score-Trimmed Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Surgical management of congenital C2 over C3 spondyloptosis with severe cervical kyphosis: two case reports.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Segment-specific versus global cervical paraspinal muscle degeneration predicts sagittal balance and functional recovery after posterior surgery.BMC musculoskeletal disorders · 2026Article
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4 authors.
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Abstract
The aim of this study was to identify relevant factors associated with sagittal malalignment, which refers to the loss of lordosis or recurrence of kyphosis following an anterior cervical approach. Degenerative cervical kyphosis has increasingly attracted clinical attention, but there are few studies about the classification of local kyphosis and risk factors of adverse sagittal alignment (ASA) after anterior surgery. The study retrospectively reviewed 82 patients with degenerative cervical myelopathy and local kyphosis who underwent anterior cervical discectomy and fusion (ACDF) between January 2019 and December 2021. The patients' baseline characteristics and postoperative assessments were reviewed using electronic medical records from a single-institution database. Based on the postoperative ASA, the patients were divided into the maintaining and adverse groups. Bivariate and multivariate statistical analyses were performed to predict related factors of the ASA. Comparing the two groups, advanced age (p = 0.019), the classification of local kyphosis (p = 0.001), and preoperative thoracic 1 (T1) slope angle (p < 0.001), C2-7 sagittal vertical axis (SVA) (p < 0.001), C2-7 range of motion (ROM) (p = 0.001), and postoperative adjacent segment degeneration (ASD) (p = 0.009), neck disability index (NDI) (p < 0.001), visual analogue score (VAS) (p < 0.001) were significantly different. Multiple linear regression analysis results for relevant factors of the change of local and C2-7 kyphosis showed classification of kyphosis (p = 0.007 and p = 0.563, respectively), T1 slope angle (p = 0.018 and p = 0.004, respectively), C2-7 SVA (p = 0.109 and p = 0.017, respectively), C2-7 ROM (p = 0.028 and p = 0.007, respectively). Our data suggest that postoperative ASA affects recovery of neck pain, and is related to preoperative T1 slope, C2-7 SVA, C2-7 ROM, and the classification of kyphosis.
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