Evidence map›Paper›PMID 40301498›Full record

ArticleScientific reports2025

Metabolites profiling of Mimusops caffra leaf via multiplex GC-MS and UPLC-MS/MS approaches in relation to its antioxidant and anti-inflammatory activities.

Mostafa H Baky, Sara M Rashad, Omayma Elgendy, Safwat A Ahmed

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Integrated Metabolomics of Processing Residues fromMolecules (Basel, Switzerland) · 2026
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mostafa H BakyDepartment of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Badr, Cairo, 11829, Egypt. dr_mostafa1984@yahoo.com.
Sara M RashadDepartment of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Badr, Cairo, 11829, Egypt.
Omayma ElgendyDepartment of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Badr, Cairo, 11829, Egypt.
Safwat A AhmedDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mimusops caffra is a small to medium-sized fruit-producing tree belonging to the Sapotaceae family with potential commercial, medicinal, and nutritional value. The main goal of the current study is to profile the phytochemical composition of M. caffra leaf targeting both volatile and non-volatile metabolites using gas chromatography and mass spectrometry (GC-MS) and ultrahigh performance liquid chromatograpy coupled with mass spectrometry (UPLC-MS/MS), respectively. A total of 62 secondary metabolites were annotated via UPLC-MS/MS belonging to organic acids, phenolic acids, flavonoids, triterpenes, fatty acids and their derivatives, and sphingolipids. Moreover, 50 volatile compounds were detected by using GC-MS classified as monoterpene, aliphatic and aromatic hydrocarbons, alcohols, phenols, fatty acids/esters, and triterpenes. The antioxidant and anti-inflammatory activities of the crude methanol extract, ethyl acetate, n-butanol fractions were evaluated using DPPH radical scavenging capacity and nitric oxide inhibition activity, respectively. The crude methanol extract exhibited the strongest antioxidant activity as compared to ethyl acetate, n-butanol fractions and ascorbic acid (used as a reference antioxidant). The IC

Indexed as

Anti-Inflammatory AgentsAntioxidantsMetabolomePlant ExtractsPlant LeavesAnimalsChromatography, High Pressure LiquidGas Chromatography-Mass SpectrometryLiquid Chromatography-Mass SpectrometryMiceNitric OxidePhytochemicalsRAW 264.7 CellsTandem Mass SpectrometryAnti-Inflammatory AgentsAntioxidantsNitric OxidePhytochemicalsPlant ExtractsAnti-inflammatoryAntioxidant activityGC-MSMimusops caffraSapotaceaeUHPLC-MS

Identifiers

PMID40301498
PMCPMC12041594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.