ArticleScientific reports2025
Pharmaceutical properties of novel 3-((diisopropylamino)methyl)-5-(4-((4-(dimethylamino) benzylidene) imino) phenyl)-1,3,4-oxadiazole-2(3 H)-thione.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Antibacterial and antibiofilm properties of 1,3,4-oxadiazoles against multidrug-resistant Pseudomonas aeruginosa isolated from burn infections - an in vitro study.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- High-fidelity machine learning models for predicting antibacterial effects of cerium oxide nanoparticles across bacterial strains.Discover nano · 2026Article
- Metabolomic and functional profiling of Lactiplantibacillus plantarum strains reveals distinct probiotic, immunomodulatory, and antimicrobial signatures.Applied microbiology and biotechnology · 2026Article
- Eco-friendly synthesis of eggshell-derived nano-hydroxyapatite: physicochemical characterization, hemocompatibility, and bone regeneration potential.Scientific reports · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
The synthesis of novel chemical compounds is crucial for developing new pharmaceuticals and antimicrobial agents. The Mannich reaction, involving Maunch bases known as carrier beta-amino-ketone molecules, is significant for producing nitrogen-containing compounds. This study investigates a new compound for its potential biological activities, particularly its antibacterial and anticancer properties. A new chemical compound, (3-((diisopropylamino)methyl)-5-(4-((4-(dimethylamino)benzylidene)imino)phenyl)-1,3,4-oxadiazole-2(3 H)-thione) (DMDBIPOT), was synthesized through the Mannich reaction, where 1,3,4-oxadiazole-2-thiol derivatives reacted with various secondary amines and formaldehyde. The compound was characterized using FTIR, 1 H NMR, and
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