Evidence map›Paper›PMID 40301357›Full record

ArticleScientific data2025

Dataset of long-term multi-site LFP activity with spontaneous chronic seizures in temporal lobe epilepsy rats.

Haoqi Ni, Yufang Yang, Fang Zhang, Yuting Sun, Yongte Zheng, Junming Zhu, Kedi Xu

Abstract readDataset
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haoqi NiZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China.ORCID http://orcid.org/0009-0003-1749-4043
Yufang YangZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China.
Fang ZhangZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China.
Yuting SunZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China.
Yongte ZhengZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China.
Junming ZhuNanhu Brain-computer interface institute, Hangzhou, 311100, China.
Kedi XuZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Key Laboratory of Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China. xukd@zju.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82272112
6 · The paper itself

Abstract

The characteristics of refractory epilepsy change with disease progression. However, relevant studies are scarce due to the difficulty in obtaining long-term multi-site data from patients with epilepsy. This work aimed to provide a long-term brain electrophysiological dataset of 15 pilocarpine-treated rats with temporal lobe epilepsy (TLE). The dataset was constituted by multi-site local field potential (LFP) signal recorded from 12 sites in the Papez circuit in TLE, including spontaneous seizures and interictal fragments in the chronic period. The LFP data were saved in MATLAB, stored in the Neurodata Without Borders format, and published on the DANDI Archive. We validated the dataset technically through specific signal analysis. In addition, we provided MATLAB codes for basic analyses of this dataset, including power spectral analysis, seizure onset pattern identification, and interictal spike detection. This dataset could reveal how the electrophysiological and epileptic network properties of the brain of rats with chronic TLE changed during epilepsy development, thus help inform the design of adaptive neuromodulation for epilepsy.

Indexed as

Epilepsy, Temporal LobeSeizuresAnimalsPilocarpineRatsPilocarpine

Identifiers

PMID40301357
PMCPMC12041466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.