ReviewActa neurologica Belgica2026
Mirror movements: mechanisms, diagnosis, and emerging therapeutic strategies.
Review in Acta neurologica Belgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
Mirror movements (MM) are involuntary, symmetrical motor actions that accompany voluntary movements of the opposite limb, arising from disruptions in corticospinal tract function and interhemispheric communication. While physiological MM occur transiently in early childhood, persistent MM are pathological and may be congenital, linked to genetic mutations affecting axon guidance, or acquired due to neurological injury. This review explores the epidemiology, classification, clinical presentation, and underlying neurophysiological mechanisms of MM, emphasizing impaired interhemispheric inhibition and abnormal corticospinal projections. Advances in electrophysiology, neuroimaging, and genetics have improved diagnostic precision, yet standardized assessment protocols remain a challenge. Current treatment strategies include motor rehabilitation, neuromodulation, and assistive interventions, with emerging approaches such as genetic therapies showing promise. A multidisciplinary framework integrating clinical, genetic, and technological advancements is essential for optimizing management and improving quality of life for individuals with MM. Further research is needed to refine diagnostic tools and explore novel therapeutic targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.