Evidence map›Paper›PMID 40301275›Full record

Observational studyHormones (Athens, Greece)2025

Evaluation of ketones intensive measurement in women with gestational diabetes (EVOKING) study.

Basilio Pintaudi, Loretta Giunta, Giacoma Di Vieste, Michela Vergani, Matteo Conti, Arianna Pani, Francesco Corrado, Rosario D'Anna, Antonino Di Benedetto

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Hormones (Athens, Greece), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Basilio PintaudiInterdisciplinary Diabetes and Pregnancy Center, Niguarda Cà Granda Hospital, Diabetology, Milan, Italy. basilio.pintaudi@ospedaleniguarda.it.
Loretta GiuntaDepartment of Clinical and Experimental Medicine, Policlinico Martino, University of Messina, Messina, Italy.
Giacoma Di ViesteInterdisciplinary Diabetes and Pregnancy Center, Niguarda Cà Granda Hospital, Diabetology, Milan, Italy.
Michela VerganiDepartment of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
Matteo ContiDepartment of Medicine and Surgery, University of Milano Bicocca, Milan, Italy.
Arianna PaniPostgraduate School of Clinical Pharmacology and Toxicology, University of Milan, Milan, Italy.
Francesco CorradoDepartment of Human Pathology, University of Messina, Messina, Italy.
Rosario D'AnnaDepartment of Human Pathology, University of Messina, Messina, Italy.
Antonino Di BenedettoDepartment of Clinical and Experimental Medicine, Policlinico Martino, University of Messina, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWomen with gestational diabetes mellitus (GDM) are frequently asked to check their ketone levels by measuring ketonuria before breakfast. However, ketosis could be present even before lunch and dinner. Furthermore, blood ketone measurement could be a more accurate test. Our aim was to evaluate the effect of a blood ketone intensive measurement in the detection of ketosis in women with GDM with a negative urinary ketone test.

methodsThis was a single center, observational, prospective study involving consecutive women with GDM. Only women with negative fasting urinary ketone tests were included. During the same gestational weeks (weeks 30-32), all women were asked to perform a blood ketone test before their main meals. Ketosis was defined as the presence for at least 25% of the time of fasting blood ketone levels > 0.1 mmol/L and > 0.2 mmol/L before lunch and dinner.

resultsOverall, a total of 101 women (mean age 34.7 ± 4.8 years, prepregnancy BMI 28.2 ± 5.2 kg/m

conclusionBlood ketone testing in women with GDM can detect a larger number of ketosis episodes than a urinary ketone test. Intensive blood ketone measurement should be recommended to women with GDM.

Indexed as

Diabetes, GestationalKetonesKetosisAdultFemaleHumansPregnancyProspective StudiesKetonesBlood glucoseBlood ketonesGestational diabetesUrinary ketones

Identifiers

PMID40301275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.