Evidence map›Paper›PMID 40301219›Full record

ArticleJournal of general internal medicine2025

Integrating Implementation Outcomes into Effectiveness Studies: A Practical Guide for Clinical Interventionists.

Danielle M Wesolowicz, William C Becker, Margarita Alegria, Lia Chin-Purcell, Joseph E Glass, Hannah K Knudsen, Patience M Dow, Karen H Seal, Emma B McGinty

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. An introduction to implementation science in rehabilitation medicine.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danielle M WesolowiczPain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, West Haven, CT, USA. danielle.wesolowicz@yale.edu.ORCID 0000-0002-3749-8450
William C BeckerPain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, West Haven, CT, USA.
Margarita AlegriaMassachusetts General Hospital, Boston, MA, USA.
Lia Chin-PurcellStanford University School of Medicine, Palo Alto, CA, USA.
Joseph E GlassKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Hannah K KnudsenDepartment of Behavioral Science, University of Kentucky, Lexington, KY, USA.
Patience M DowDepartment of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, RI, USA.
Karen H SealIntegrative Health Service, San Francisco Veterans Affairs Health Care System, San Francisco, CA, USA.
Emma B McGintyDivision of Health Policy and Economics, Weill Cornell Medical College, New York City, NY, USA.

Funding

Use of topic modeling and stakeholderengagement to map determinants of implementation disparities in addiction and pain researchU2CDA057717 · NIDA · STANFORD UNIVERSITY · PI C. HENDRICKS BROWN · 2022 to 2026
$19.1M
Transforming health equity rhetoric to rigor: Development and validation of a novel measure assessing health equity in implementation of health interventionsP50DA054072 · NIDA · STANFORD UNIVERSITY · PI Mark P McGovern · 2022 to 2026
$18.1M
Using an innovative quality improvement process to increase delivery of evidenced-based CVD risk factor care in community mental health organizationsP50MH115842 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Christina T. Yuan · 2018 to 2026
$16.2M
Intramural Research Program, National Institute on Drug Abuse P50DA054072Intramural Research Program, National Institute on Drug Abuse U2CDA057717NIDA NIH HHS P50 DA054072NIDA NIH HHS U2C DA057717NIMH NIH HHS P50 MH115842
6 · The paper itself

Abstract

Designing effectiveness studies with implementation in mind can allow interventionists to translate their research into real-world practice. Implementation outcomes measure how much and how well a particular intervention was implemented and can provide valuable insights into any heterogeneity in effectiveness outcomes. As part of the National Institutes of Health's (NIH) Helping to End Addiction Long-term® (HEAL) Initiative's Data2Action program, a workgroup of the Research Adoption Support Center (RASC) was tasked with creating a resource guide to aid clinical interventionists in integrating implementation outcomes into their research plans. This paper aims to provide a plain-language, pragmatic guide to implementation outcomes for clinical interventionists, including key considerations for each outcome and examples of implementation-effectiveness studies that reported implementation outcomes. We conclude by discussing the limitations of our guide and implementation outcome reporting more broadly. We offer suggestions for implementation scientists and clinical interventionists to work toward a common goal of improved implementation outcome reporting.

Indexed as

Outcome Assessment, Health CareHumansImplementation ScienceUnited Statesacceptabilityadoptioneffectivenessfeasibilityimplementation

Identifiers

PMID40301219
PMCPMC12344027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.