Evidence map›Paper›PMID 40301216›Full record

ArticleJournal of general internal medicine2025

Impact of Mental Health Disorders in Patients with Myocardial Infarction with Non-obstructive Coronary Arteries: A Propensity Score-Matched Nationwide Analysis.

Abdul Rasheed Bahar, Paawanjot Kaur, Yasemin Bahar, Ryan Berry, Yasaman Navari, Mohamed S Alrayyashi, Olayiwola Bolaji, Wael AlJaroudi, M Chadi Alraies

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Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Abdul Rasheed BaharDepartment of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, USA.
Paawanjot KaurDepartment of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, USA.
Yasemin BaharDepartment of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, USA.
Ryan BerryAuthority Health, Detroit, MI, USA.
Yasaman NavariMichigan State University, Flint, MI, USA.
Mohamed S AlrayyashiDepartment of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, USA.
Olayiwola BolajiUniversity of Maryland Capital Region Medical Center, Largo, MD, USA.
Wael AlJaroudiDepartment of Cardiology, Medical College of Georgia at Augusta University, Augusta, GA, USA.
M Chadi AlraiesCardiovascular Institute, Detroit Medical Center, Wayne State University, Detroit, MI, USA. alraies@hotmail.com.ORCID 0000-0002-7874-4566

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyocardial infarction with non-obstructive coronary arteries (MINOCA) is defined by myocardial infarction criteria with < 50% stenosis and no clear cause. While mental health disorders are linked to cardiovascular risk, their impact on MINOCA outcomes is not well studied.

methodsWe conducted a retrospective cohort study using the National Inpatient Sample (NIS) from 2017 to 2021, identifying hospitalized MINOCA patients with and without mental health disorders using ICD-10-CM codes. Propensity score matching and inverse probability weighting (IPW) were employed to adjust for confounders and balance baseline characteristics. Multivariable logistic regression estimated adjusted odds ratios and 95% confidence intervals for in-hospital outcomes.

resultsAmong 4300 propensity-matched pairs (8600 patients), MINOCA patients with mental health disorders had higher in-hospital mortality (2.26% vs 1.21%, p < 0.001) and increased risk of sudden cardiac arrest (1.51% vs 0.65%, p < 0.001). They were also more likely to develop pulmonary embolism (1.54% vs 0.65%, p < 0.001) and acute kidney injury (25.45% vs 20.24%, p < 0.001).

conclusionMental health disorders are independently associated with higher in-hospital mortality and adverse cardiovascular outcomes among MINOCA patients. These findings highlight the urgent need for integrated cardiovascular and psychiatric care, emphasizing early screening, multidisciplinary management, and targeted interventions to improve patient outcomes.

Indexed as

Mental DisordersMyocardial InfarctionAgedFemaleHospital MortalityHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesUnited StatesIn-hospital mortalityMental health disordersMyocardial infarctionNon-obstructive coronary artery disease

Identifiers

PMID40301216
PMCPMC12612494

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.