Evidence map›Paper›PMID 40301178›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Refractive changes after cataract removal in infancy: comparing eyes with and without persistent fetal vasculature.

Ana Navarrete, Brice Nguedia Vofo, Hadas Mechoulam, Milka Matanis-Suidan, Nur Azem, Ilana Karshai, Ran David, Irene Anteby

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ana NavarreteDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel. anacarolinanavarrete@gmail.com.ORCID http://orcid.org/0000-0002-2844-9382
Brice Nguedia VofoDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.
Hadas MechoulamDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.ORCID http://orcid.org/0000-0002-5437-8426
Milka Matanis-SuidanDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.
Nur AzemDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.
Ilana KarshaiDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.
Ran DavidDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.
Irene AntebyDepartment of Ophthalmology, Hadassah-Hebrew University Medical Center, Kalman Ya'Akov Man Street, POB 12000, Jerusalem, 91120, Israel.ORCID http://orcid.org/0000-0001-6878-0443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the refractive changes after congenital cataract surgery in persistent fetal vasculature (PFV) vs. non-PFV eyes.

methodsRetrospective study of 75 eyes with PFV or non-PFV congenital cataract, who underwent surgery before age 7 months (unilateral/first operated eye), during 2007-2018 at a tertiary referral center, with follow-up ≥ one-year.

results27 eyes (36%) had PFV, 48 were non-PFV cataracts. Mean age (± SD) at surgery in children with PFV was 2.24 ± 1.23 months and 2.44 ± 1.51 months in the non-PFV group. Mean post-operative follow-up was 64.94 ± 34.67 months. 60% of the eyes remained aphakic for the entire follow-up. In aphakic children, the mean post-operative spherical equivalent (SE) in the PFV eye was + 18.74D, + 15.73D, + 13.88D, + 12.51D, + 11.29D at one-month, one-year, two-years, three-years and five-years respectively. In the non-PFV eye the SE was + 23.00D, + 20.44D, + 17.84D, + 17.52D, + 18.48D at one-month, one-year, two-years, three-years and five-years respectively. During the entire post-operative course, the SE remained less hyperopic in the PFV eyes (p < 0.01). The rate of emmetropization was similar for PFV and non-PFV eyes. Five-years after surgery the mean myopic shift was -6.82 ± 4.32 D in the PFV eyes and -5.47 ± 2.44D in the non-PFV eyes (p > 0.05). The changes in refraction error did not correlate with either presence of glaucoma, secondary cataract, amblyopia or strabismus.

conclusionEyes with PFV have a similar rate of emmetropization as other pediatric congenital cataracts. Interestingly, aphakic PFV eyes have a less hyperopic refraction during one-month and up to five-years after surgery as compared to non-PFV eyes.

Indexed as

CataractCataract ExtractionPersistent Hyperplastic Primary VitreousRefraction, OcularVisual AcuityChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesEmmetropizationPediatric cataractPersistent fetal vasculatureRefractive errors

Identifiers

PMID40301178
PMCPMC12414064

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.