Evidence map›Paper›PMID 40301166›Full record

ArticleSurgery today2025

The minimum apparent diffusion coefficient value on preoperative magnetic resonance imaging in resectable pancreatic cancer: a new prognostic factor for biologically borderline resectable pancreatic cancer.

Michinori Matsumoto, Masashi Tsunematsu, Ryoga Hamura, Koichiro Haruki, Kenei Furukawa, Yoshihiro Shirai, Tadashi Uwagawa, Shinji Onda, Tomohiko Taniai, Yoshiaki Tanji and 2 more

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Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Prognostic Significance of Preoperative StagingMolecular imaging and radionuclide therapy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michinori MatsumotoDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan. mmatsumoto4@jikei.ac.jp.ORCID http://orcid.org/0000-0002-5860-1103
Masashi TsunematsuDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Ryoga HamuraDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Koichiro HarukiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Kenei FurukawaDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Yoshihiro ShiraiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Tadashi UwagawaDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Shinji OndaDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Tomohiko TaniaiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Yoshiaki TanjiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Mitsuru YanagakiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.
Toru IkegamiDepartment of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-Ku, Tokyo, 105-8461, Japan.

Funding

Japan Society for the Promotion of Science 22K16453Japan Society for the Promotion of Science 22K16523Japan Society for the Promotion of Science 23K08202Japan Society for the Promotion of Science 23K08222Japan Society for the Promotion of Science 23K15483Japan Society for the Promotion of Science 23K15531Japan Society for the Promotion of Science 24K11857Japan Society for the Promotion of Science 24K11898Japan Society for the Promotion of Science 24K11920Japan Society for the Promotion of Science 24K19377
6 · The paper itself

Abstract

purposeTo identify the prognostic factors that can define biologically borderline resectable pancreatic cancer (BRPC) in resectable pancreatic cancer (RPC) patients.

methodsThis retrospective study included 121 R/BRPC patients who underwent upfront surgery. Univariate and multivariate analyses were conducted to investigate the relationship between preoperative factors and overall survival (OS) for RPC. The OS of RPC patients was stratified based on a score, with each independent prognostic factor receiving 1 point. The OS of the R/BRPC patients was compared based on their scores.

resultsOverall, 113 and eight patients had RPC and BRPC. Serum CA19-9 > 500 U/mL (p = 0.048), maximum tumor diameter > 30 mm (p = 0.01), superior mesenteric/portal vein contact < 180° (p = 0.04), and minimum apparent diffusion coefficient (ADC

conclusionsPreoperative ADC

Indexed as

Diffusion Magnetic Resonance ImagingPancreatic NeoplasmsAdultAgedAged, 80 and overBiomarkers, TumorCA-19-9 AntigenFemaleHumansMaleMiddle AgedPreoperative CarePreoperative PeriodPrognosisRetrospective StudiesSurvival RateBiomarkers, TumorCA-19-9 AntigenApparent diffusion coefficientBiological borderline resectable pancreatic cancerMagnetic resonance imagingPancreatic cancer

Identifiers

PMID40301166

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.