Evidence map›Paper›PMID 40301153›Full record

ArticleWorld journal of pediatrics : WJP2025

Impact of lateral positioning on upper airway morphology in sedated children under five.

Hui Li, Xuan Jia, Hui Ye, Jia-Wei Liang, Wen-Li Zhao, Ping Cui, Yaqi Sun, Deng-Ming Lai, Qiang Shu, Yue Jin and 2 more

Abstract read
In one paragraph

Article in World journal of pediatrics : WJP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hui LiDepartment of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Wenyixi Road 1367, Hangzhou, 311121, China.
Xuan JiaDepartment of Radiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Hui YeChildren's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Jia-Wei LiangDepartment of Radiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Wen-Li ZhaoDepartment of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Wenyixi Road 1367, Hangzhou, 311121, China.
Ping CuiDepartment of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Wenyixi Road 1367, Hangzhou, 311121, China.
Yaqi SunDepartment of Hematology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Deng-Ming LaiDepartment of Neonatal Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Qiang ShuDepartment of Thoracic and Cardiovascular Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Yue JinDepartment of Anesthesiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310003, China.
Guo-Hao XieDepartment of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Wenyixi Road 1367, Hangzhou, 311121, China.
Xiang-Ming FangDepartment of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Wenyixi Road 1367, Hangzhou, 311121, China. xmfang@zju.edu.cn.ORCID 0000-0002-2283-1863

Funding

Key Research and Development Program of Zhejiang Province 2022C03163National Natural Science Foundation of China 82302425National Natural Science Foundation of China 82372184
6 · The paper itself

Abstract

backgroundThe upper airway morphology in children varies with age and body position. This study aimed to analyze the impact of lateral positioning on the upper airway of sedated children under five.

methodsThis retrospective study included pediatric patients who underwent MRI in both the supine and lateral positions at Children's Hospital, Zhejiang University School of Medicine. Upper airway morphology was reconstructed using 3D Slicer software. Python was employed to estimate cross-sectional areas via pixel analysis. The narrowest cross-sectional area, minimal transverse and anteroposterior diameters, airway length, and airway volume were measured and stratified by age for subgroup analysis.

resultsIn sedated children under 5 years old and when compared to the supine position, lateral positioning increased minimal transverse diameter by 18.70% (P = 0.001), narrowest cross-sectional area by 49.21% (P < 0.001), anteroposterior diameter by 25.54% (P < 0.001), airway volume by 65.64% (P < 0.001), and airway length by 11.93% (P < 0.001). In all subgroups, lateral positioning significantly increased the narrowest cross-sectional area, airway length, and airway volume. However, minimal anteroposterior diameter in the 1-to 3-year age group and minimal transverse diameter in the 3 -to 5-year age group tended to increase in the lateral position but did not reach statistical significance.

conclusionsLateral position significantly enlarges the upper airway in sedated children under five. These findings support using lateral position to enhance airway patency in younger patients.

Indexed as

Patient PositioningProcedural SedationChild, PreschoolFemaleHumansImaging, Three-DimensionalInfantMagnetic Resonance ImagingMaleRetrospective StudiesSupine PositionChildren Lateral position Three-dimensional modelUnder 5 years oldUpper airway

Identifiers

PMID40301153
PMCPMC12245947

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.