Evidence map›Paper›PMID 40301035›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Metachronous Occurrence of Mucosa-associated Lymphoid Tissue (MALT) Lymphoma in the Esophagus and Tonsillar Diffuse Large B-cell Lymphoma 18 Years After Helicobacter pylori Eradication for Gastric MALT Lymphoma.

Hourin Cho, Eri Iwata, Ryota Niikura, Mariko Hamada, Yoshika Akimoto, Naoyoshi Nagata, Akihiko Gotoh, Jun Matsubayashi, Naoya Nakamura, Kiyoaki Tsukahara and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hourin ChoDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.
Eri IwataDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.
Ryota NiikuraDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.
Mariko HamadaDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.
Yoshika AkimotoDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.
Naoyoshi NagataDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.
Akihiko GotohDepartment of Hematology, Tokyo Medical University, Japan.
Jun MatsubayashiDepartment of Anatomic Pathology, Tokyo Medical University, Japan.
Naoya NakamuraDepartment of Pathology, Tokai University School of Medicine, Japan.
Kiyoaki TsukaharaDepartment of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Japan.
Takao ItoiDepartment of Gastroenterology and Hepatology, Tokyo Medical University, Japan.
Koichiro AbeDepartment of Radiology, Tokyo Medical University, Japan.
Takashi KawaiDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 51-year-old man was diagnosed with gastric mucosa-associated lymphoid tissue (MALT) lymphoma after presenting with fold convergence on upper gastrointestinal radiography and nausea. He tested positive for Helicobacter pylori, and eradication therapy decreased the size of the gastric MALT lymphoma. Eighteen years later, whitish subepithelial lesions were discovered in the middle thoracic esophagus which were diagnosed to be esophageal MALT lymphoma. Six months later, the left tonsillar swelling was identified as diffuse large B-cell lymphoma (DLBCL). Complete remission was achieved after treatment with rituximab and chemotherapy. To our knowledge, this is the first reported case of metachronous gastric and esophageal MALT lymphoma with tonsillar DLBCL.

Indexed as

Esophageal NeoplasmsHelicobacter InfectionsHelicobacter pyloriLymphoma, B-Cell, Marginal ZoneLymphoma, Large B-Cell, DiffuseNeoplasms, Second PrimaryStomach NeoplasmsTonsillar NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsHumansMaleMiddle AgedRituximabRituximabdiffuse large B-cell lymphomaesophagusmucosa-associated lymphoid tissue lymphomastomachtonsil

Identifiers

PMID40301035
PMCPMC12659940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.