Evidence map›Paper›PMID 40300861›Full record

ArticleTherapeutic drug monitoring2025

Exploring Health Care Professionals' Engagement With a Precision Dosing Calculator and Supporting Clinical Information: Insights From an Eye-Tracking and Usability Study.

Sherilyn Wong, Philip R Selby, Michael B Ward, Stephanie E Reuter

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Article in Therapeutic drug monitoring, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sherilyn WongUniSA Clinical and Health Sciences, University of South Australia, Adelaide, Australia; and.ORCID 0000-0001-7426-2116
Philip R SelbyUniSA Clinical and Health Sciences, University of South Australia, Adelaide, Australia; and.
Michael B WardUniSA Clinical and Health Sciences, University of South Australia, Adelaide, Australia; and.
Stephanie E ReuterUniSA Clinical and Health Sciences, University of South Australia, Adelaide, Australia; and.

Funding

Australian Government Research Training Program (RTP)
6 · The paper itself

Abstract

backgroundPharmacokinetic-based dosing calculators for individualized drug dosing remain underutilized in clinical practice, often due to poor usability and a lack of user-centered design. Understanding how health care professionals interact with these tools can inform design strategies and enhance usability.

methodsHealth care professionals wore eye-tracking glasses while using a codesigned vancomycin dosing calculator with supporting clinical information to complete example clinical scenarios. Eye-tracking data were collected for 23 predefined areas of interest, and fixation sequences were analyzed. A Post-Study System Usability Questionnaire was administered to assess the tool's perceived usability.

resultsEleven pharmacists and three doctors participated in the study. The highest average dwell times were recorded for the pharmacokinetic plot, dosage regimen selection, dosing history, drug concentrations, and the area under the concentration-time curve and dose visualization area. Participants generally viewed patient demographic information first and pharmacokinetic and dosage regimen information last. Considerable heterogeneity was observed among participants' fixation sequences, with frequent eye movements between key areas, particularly between the pharmacokinetic plot and dosage regimen selection, and between dosing history and drug concentrations. Participants expressed a preference for these elements to be positioned close together.

conclusionsUnderstanding how health care professionals interact with decision support systems is essential for developing user-friendly tools that align with clinical workflows. Eye-tracking data provided valuable insights into user engagement patterns with the dosing calculator and clinical information interface. These insights will guide future design strategies to address usability barriers that limit the utilization of dosing calculators in clinical practice and promote the implementation of individualized drug dosing.

Indexed as

Drug Dosage CalculationsEye-Tracking TechnologyHealth PersonnelVancomycinAdultAnti-Bacterial AgentsEye MovementsFemaleHumansMaleMiddle AgedPharmacistsPrecision MedicineSurveys and QuestionnairesAnti-Bacterial AgentsVancomycindosing softwareeye-trackingindividualized dosingtherapeutic drug monitoringusability

Identifiers

PMID40300861
PMCPMC12588662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.