Evidence map›Paper›PMID 40300712›Full record

ArticleContemporary clinical trials2025

Workforce and systems change to treat adolescent substance use disorder within integrated pediatric primary care: A cluster-randomized stepped-wedge trial.

Leslie A Hulvershorn, Matthew Aalsma, Trey V Dellucci, Ashlyn Burns, Brigid R Marriott, Bernice Pescosolido, Harold D Green, Lisa Saldana, Jason Chapman, Patrick Monahan and 3 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Leslie A HulvershornAdolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Matthew AalsmaAdolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Trey V DellucciAdolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Ashlyn BurnsAdolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Brigid R MarriottAdolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Bernice PescosolidoIrsay Institute, Indiana University, Bloomington, IN, USA; Department of Sociology, Indiana University, Bloomington, IN, USA.
Harold D GreenIrsay Institute, Indiana University, Bloomington, IN, USA; Department of Applied Health Science, Indiana University School of Public Health, Bloomington, IN, USA.
Lisa SaldanaChestnut Health Systems, Eugene, OR, 1255, Pearl Street, Ste 101, United States of America.
Jason ChapmanChestnut Health Systems, Eugene, OR, 1255, Pearl Street, Ste 101, United States of America.
Patrick MonahanDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA.
Sarah E WieheDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Edward J MiechDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Zachary W AdamsAdolescent Behavioral Health Research Program, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: zwadams@iu.edu.

Funding

Workforce and System Change to Treat Adolescent Opioid Use Disorder within Integrated Pediatric Primary CareR33DA059948 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI Matthew Aalsma, Zachary William Adams · 2024 to 2026
$3.8M
Workforce and System Change to Treat Adolescent Opioid Use Disorder within Integrated Pediatric Primary CareR61DA059948 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI AALSMA, MATTHEW, ADAMS, ZACHARY WILLIAM · 2023 to 2023
$573k
NIDA NIH HHS R33 DA059948NIDA NIH HHS R61 DA059948
6 · The paper itself

Abstract

backgroundWhile the overdose crisis has impacted all ages, overdose-related deaths among adolescents have been increasing more rapidly than any other age group, doubling between 2019 and 2020. Identifying and treating substance use disorders (SUDs) among adolescents is critical to preventing adolescent overdose deaths. While evidence-based interventions for adolescents with SUDs exist, they remain underutilized. Implementing SUD interventions in primary care settings through integrated behavioral health (IBH) is one approach for increasing access to evidence-based SUD services for adolescents.

methodsThis is a Hybrid Type 2, cluster-randomized, stepped-wedge trial comparing SUD IBH to standard primary care treatment. In our open cohort stepped-wedge design, primary care clinics will be randomly designated to one of three cohorts. We will use a mixed-methods approach to evaluate both implementation and effectiveness outcomes, with a focus on assessing the impact of IBH on primary care provider behaviors around SUD interventions. All cohorts will complete baseline surveys during the control condition and then every 6 months. At each time point, we will also collect and analyze patient administrative data to assess patient engagement and outcomes. In addition, we will conduct qualitative interviews at pre-, mid-, and post-implementation during sustainment of the intervention.

conclusionAddressing the overdose crisis is a national priority. IBH has the potential to reduce overdose rates by enhancing primary care provider willingness to deliver SUD services for adolescents.

Indexed as

Delivery of Health Care, IntegratedDrug OverdosePrimary Health CareSubstance-Related DisordersAdolescentFemaleHumansMaleRandomized Controlled Trials as TopicAdolescentsIntegrated behavioral healthOverdoseSubstance use disorder

Identifiers

PMID40300712
PMCPMC12215800

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.