Evidence map›Paper›PMID 40300635›Full record

ArticleJournal of the Royal Society, Interface2025

A systematic evaluation of the language-of-viral-escape model using multiple machine learning frameworks.

Brent E Allman, Luiz Vieira, Daniel J Diaz, Claus O Wilke

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Predicting high-fitness viral protein variants with Bayesian active learning and biophysics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brent E AllmanIntegrative Biology, The University of Texas at Austin, Austin, Texas, USA.
Luiz VieiraIntegrative Biology, The University of Texas at Austin, Austin, Texas, USA.
Daniel J DiazInstitute for Foundations of Machine Learning, The University of Texas at Austin, Austin, Texas, USA.
Claus O WilkeIntegrative Biology, The University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0002-7470-9261

Funding

Division of Environmental Biology
6 · The paper itself

Abstract

Predicting the evolutionary patterns of emerging and endemic viruses is key for mitigating their spread. In particular, it is critical to rapidly identify mutations with the potential for immune escape or increased disease burden. Knowing which circulating mutations pose a concern can inform treatment or mitigation strategies such as alternative vaccines or targeted social distancing. In 2021, Hie B, Zhong ED, Berger B, Bryson B. 2021 Learning the language of viral evolution and escape.

Indexed as

Machine LearningNatural Language ProcessingViral ProteinsHumansMutationViral Proteinsimmune escapemachine learningprotein language modelsSARS-CoV-2

Identifiers

PMID40300635
PMCPMC12040448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.