ArticleThe Journal of surgical research2025
Predictors of Cumulative 90-D Mortality for Septic Patients Undergoing Abdominal Surgery.
Article in The Journal of surgical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Contextual nonmedical health factors and critical care-related outcomes: a systematic review.Critical care (London, England) · 2025Pooled it
- Obesity Attenuates the Association Between the Modified Five-Item Frailty Score and Mortality in Septic Surgical Patients.The Journal of surgical research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
introductionSeptic surgical patients undergoing emergency general surgery represent a distinct population with unique challenges. This study aimed to identify predictors of cumulative 90-d mortality, including clinical and socioeconomic factors, and to analyze causes of death in this cohort.
methodsA retrospective analysis was conducted on patients admitted to a surgical intensive care unit from 2011 to 2019 with sepsis (sequential organ failure assessment score ≥2) undergoing emergency intra-abdominal surgery (n = 498). Demographics, comorbidities, sepsis presentation, and socioeconomic metrics, including the area deprivation index (ADI), were analyzed. Independent predictors of mortality were identified using multiple logistic regression. The causes of death were categorized and analyzed.
resultsAmong 498 patients, 46% (n = 229) died within 90 d. Nonsurvivors were older (65 ± 13.7 versus 61.2 ± 13.5 y, P < 0.01), more often transferred from external facilities (59% versus 46%, P < 0.01), and had higher rates of liver disease, chronic kidney disease, metastatic cancer, obesity, and higher Charlson comorbidity index scores (P < 0.01 for all). Independent predictors of 90-d mortality included admission sequential organ failure assessment scores, serum lactate, obesity, ADI, Charlson comorbidity index, and transfer status. ADI remained a significant predictor, while the distressed communities index did not. Of the deaths, 76.9% were in-hospital deaths, with intra-abdominal catastrophes (35.4%), multisystem organ failure (25.2%), and pulmonary causes (16.4%) as the most common causes.
conclusionsIntra-abdominal catastrophes, multiorgan failure, and pulmonary complications are leading causes of death in septic emergency general surgery patients. ADI is a robust socioeconomic predictor of mortality, underscoring the need for integrating social determinants into risk assessment and tailored care strategies. Developing comprehensive risk models may enhance prognostication and guide clinical decision-making in this critical population.
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