Evidence map›Paper›PMID 40300246›Full record

SynthesisInternational journal of hygiene and environmental health2025

Long-term exposure to criteria air pollutants and infant mortality: a systematic review and meta-analysis.

Adrien A Wilkie, Alison K Krajewski, Fanny Njie, Kevin Park, Sarah Zelasky, Kristen M Rappazzo, Thomas J Luben

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of hygiene and environmental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adrien A WilkieOak Ridge Institute for Science and Education (ORISE) at the U.S. Environmental Protection Agency, RTP, North Carolina, USA; U.S. Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessment, RTP, North Carolina, USA. Electronic address: wilkie.adrien@epa.gov.
Alison K KrajewskiU.S. Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessment, RTP, North Carolina, USA.
Fanny NjieOak Ridge Associated Universities (ORAU) at the U.S. Environmental Protection Agency, RTP, North Carolina, USA.
Kevin ParkOak Ridge Associated Universities (ORAU) at the U.S. Environmental Protection Agency, RTP, North Carolina, USA.
Sarah ZelaskyOak Ridge Associated Universities (ORAU) at the U.S. Environmental Protection Agency, RTP, North Carolina, USA.
Kristen M RappazzoU.S. Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessment, RTP, North Carolina, USA.
Thomas J LubenU.S. Environmental Protection Agency, Office of Research and Development, Center for Public Health and Environmental Assessment, RTP, North Carolina, USA.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

aimWe conducted a systematic review/meta-analysis for epidemiologic evidence of the association between long-term criteria air pollution (nitrogen dioxide (NO

methodsStudies were identified through PubMed/Web of Science databases using comprehensive search terms, then screened using predefined criteria. For studies eligible for inclusion in meta-analyses, we applied a systematic rubric for evaluating study quality across domains: participant selection, outcome, exposure, confounding, analysis, selective reporting, sensitivity, overall quality. When ≥3 eligible studies provided effect estimates, we performed meta-analyses to estimate pooled odds ratios (ORs) and 95% confidence intervals (95% CI) for air pollutants and infant mortality.

resultsOf the 701 initial studies, we excluded 678 studies in the abstract screening and full text screening phases, leaving 23 studies for inclusion. Four studies included extractable effect estimates for PM

conclusionsLong-term exposure to PM

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureInfant MortalityHumansInfantInfant, NewbornOzoneParticulate MatterSudden Infant DeathSulfur DioxideAir PollutantsOzoneParticulate MatterSulfur DioxideAir pollutionInfant mortalityLong-term exposureMeta-analysisSystematic review

Identifiers

PMID40300246
PMCPMC12146862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.