Evidence map›Paper›PMID 40300180›Full record

ArticleJMIR infodemiology2025

#GenderAffirmingHormoneTherapy and Health Information on TikTok: Thematic Content Analysis.

Julia Rose Beatini, Nora Yanyi Sun, Julianna K Coleman, Maetal E Haas-Kogan, Andrea Pelletier, Deborah Bartz, Alex Sogomon Keuroghlian

Abstract read
In one paragraph

Article in JMIR infodemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia Rose Beatini *Thomas Jefferson University, Philadelphia, PA, United States.ORCID 0000-0003-1901-4472
Nora Yanyi Sun *Harvard University, Cambridge, MA, United States.ORCID 0009-0008-2023-8215
Julianna K ColemanHarvard Medical School, Boston, MA, United States.ORCID 0000-0003-2784-0221
Maetal E Haas-KoganHarvard Medical School, Boston, MA, United States.ORCID 0000-0003-2288-9851
Andrea PelletierHarvard Medical School, Boston, MA, United States.ORCID 0000-0003-3063-2968
Deborah BartzHarvard Medical School, Boston, MA, United States.ORCID 0000-0002-3096-9715
Alex Sogomon KeuroghlianHarvard Medical School, Boston, MA, United States.ORCID 0000-0002-6624-8354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transgender and gender diverse people often turn to online platforms for information and support regarding gender-affirming hormone therapy (GAHT); however, analysis of this social media content remains scarce. Objective: We characterized GAHT-related videos on TikTok to highlight the implications relevant to GAHT prescribers. Methods: We used a web scraper to identify TikTok videos posted under the hashtags #genderaffirminghormonetherapy and #genderaffirminghormones as of November 2023. We identified recurrent themes via qualitative content analysis and assessed health education videos with the Patient Education Materials Assessment Tool for Audiovisual Materials (PEMAT-A/V) scale and a modified Currency, Relevance, Authority, Accuracy, and Purpose (CRAAP) test. Results: Out of 69 videos extracted, 71% (49/69) were created by GAHT users, 24.6% (17/69) were created by health care workers, and 21.7% (15/69) were created to provide health education. Themes included physical changes on testosterone, GAHT access, and combating misinformation and stigma surrounding GAHT. Health education videos scored highly on PEMAT-A/V items assessing understandability (mean 88.3%, SD 11.3%) and lower on actionability (mean 60.0%, SD 45.8%). On the CRAAP test, videos scored highly on the relevance, authority, and purpose domains but lower on the currency and accuracy domains. Conclusions: Discussions of GAHT on TikTok build community among transgender and gender diverse users, provide a platform for digital activism and resistance against legislation that limits GAHT access, and foster patient-provider dialogue. Educational videos are highly understandable and are created by reliable sources, but they vary in terms of currency and quality of supporting evidence, and they lack in actionability.

Indexed as

Gender-Affirming ProceduresPatient Education as TopicSocial MediaTransgender PersonsFemaleHumansMaleVideo Recordingaudiovisual materialsCRAAPCurrency, Relevance, Authority, Accuracy, and PurposeGAHTgender affirminggender-affirming hormone therapygender diversegender fluidhashtaghormone therapymedia informationonline platformpatient education materials assessmentPEMATqualitativequalitative content analysissocial mediasocial media analysissocial media contentTGDthemesTikToktransgendertransgender and gender diverseweb scraper

Identifiers

PMID40300180
PMCPMC12054967

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.